STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C5DNS8_LACTCL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (327 aa)    
Predicted Functional Partners:
C5DG09_LACTC
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.965
C5E2P3_LACTC
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
 0.950
C5DGI0_LACTC
Aspartate aminotransferase.
   
 0.949
C5DGC6_LACTC
Aspartate aminotransferase.
   
 0.947
C5DGN4_LACTC
Malic enzyme.
  
 0.942
C5E2N9_LACTC
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
   
 0.928
C5DN45_LACTC
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 0.915
C5DES6_LACTC
KLTH0C11770p.
   
 
 0.913
C5DES8_LACTC
KLTH0C11858p.
   
 
 0.913
C5DCP6_LACTC
KLTH0B04774p.
   
 
 0.912
Your Current Organism:
Lachancea thermotolerans
NCBI taxonomy Id: 559295
Other names: Kluyveromyces thermotolerans CBS 6340, L. thermotolerans CBS 6340, Lachancea thermotolerans CBS 6340
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.