STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sucCsuccinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (389 aa)    
Predicted Functional Partners:
sucD
succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 0.999
SDZ08432.1
2-oxoglutarate dehydrogenase E1 component.
 0.999
SDZ40458.1
Succinate dehydrogenase subunit B; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
 0.991
SDZ40491.1
Succinate dehydrogenase subunit C.
  
 
 0.990
SDZ02669.1
2-oxoglutarate dehydrogenase E2 component.
 0.986
SDZ40481.1
Succinate dehydrogenase subunit D.
  
 
 0.983
SDZ04509.1
Glutamate synthase (NADH) large subunit.
   
 
 0.973
SDZ40470.1
Succinate dehydrogenase subunit A.
 0.973
SDY81689.1
Succinate dehydrogenase / fumarate reductase flavoprotein subunit.
 0.969
SDZ49002.1
Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.
  
 0.956
Your Current Organism:
Herbiconiux ginsengi
NCBI taxonomy Id: 381665
Other names: CGMCC 4.3491, DSM 19088, H. ginsengi, Herbiconiux ginsengi (Qiu et al. 2007) Behrendt et al. 2011, JCM 13908, Leifsonia ginsengi, Leifsonia ginsengi Qiu et al. 2007, Leifsonia sp. wged11, NBRC 104580, strain wged11
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.