STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bktBAcetyl-CoA acetyltransferase; Required for efficient production of poly(beta- hydroxybutyrate-co-beta-hydroxyvalerate) (PHBV). Catalyzes the condensation of acetyl-CoA and propionyl-CoA to form beta-ketovaleryl- CoA, and the condensation of two acetyl-CoA molecules to form acetoacetyl-CoA; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)    
Predicted Functional Partners:
h16_A1526
Enoyl-CoA hydratase/Delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase.
 
 0.972
h16_A0461
Two domain protein: 3-hydroxyacyl-CoA dehydrogenase.
  
 0.969
pct
Propionate CoA-transferase; CoA transferase having broad substrate specificity for short- chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons. Belongs to the 3-oxoacid CoA-transferase family.
 
  
 0.959
paaH1
3-Hydroxyacyl-CoA dehydrogenase.
 0.955
paaH2
3-Hydroxyacyl-CoA dehydrogenase.
 0.936
h16_A2860
Acetoacetyl-CoA synthetase.
  
 
 0.931
aceB
Malate synthase; Belongs to the malate synthase family.
   
 
 0.928
h16_A1358
Acetyl-CoA hydrolase.
  
 
 0.911
h16_B0358
Acyl-CoA synthetase.
  
 
 0.911
h16_B1368
Acetyl-CoA hydrolase/transferase.
  
 
 0.911
Your Current Organism:
Cupriavidus necator
NCBI taxonomy Id: 381666
Other names: Alcaligenes eutropha H16, C. necator H16, Cupriavidus necator ATCC 17699, Cupriavidus necator H16, Ralstonia eutropha ATCC 17699, Ralstonia eutropha H16, Ralstonia eutropha str. H16, Ralstonia eutropha strain H16, Wautersia eutropha H16
Server load: low (38%) [HD]