STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ptpS6-Pyruvoyl tetrahydrobiopterin synthase protein. (158 aa)    
Predicted Functional Partners:
h16_A1925
Organic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
 
 
 0.995
folE
GTP cyclohydrolase I.
  
 
 0.984
exsB
Predicted PP-loop superfamily ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.
 
  
 0.939
h16_A2731
Uncharacterized conserved protein; Converts GTP to 7,8-dihydroneopterin triphosphate.
    
 0.928
h16_A0455
dATP pyrophosphohydrolase.
    
  0.904
phoD
Phosphodiesterase/alkaline phosphatase D.
    
  0.903
h16_A2182
Alkaline phosphatase; Belongs to the alkaline phosphatase family.
     
  0.900
h16_A2183
Alkaline phosphatase; Unknown EC_number=3.1.3.1-; Belongs to the alkaline phosphatase family.
     
  0.900
h16_A0426
Enzyme related to GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
  
  
 0.858
mccF
Putative muramoyl-tetrapeptide carboxypeptidase,homologs of microcin C7 resistance protein MccF.
       0.786
Your Current Organism:
Cupriavidus necator
NCBI taxonomy Id: 381666
Other names: Alcaligenes eutropha H16, C. necator H16, Cupriavidus necator ATCC 17699, Cupriavidus necator H16, Ralstonia eutropha ATCC 17699, Ralstonia eutropha H16, Ralstonia eutropha str. H16, Ralstonia eutropha strain H16, Wautersia eutropha H16
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