node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
chrB | exsB | H16_B1482 | H16_A2826 | Chromate resistance protein ChrB. | Predicted PP-loop superfamily ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.608 |
chrB | h16_A1925 | H16_B1482 | H16_A1925 | Chromate resistance protein ChrB. | Organic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.662 |
chrB | tpx | H16_B1482 | H16_A3175 | Chromate resistance protein ChrB. | Thiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily. | 0.646 |
exsB | chrB | H16_A2826 | H16_B1482 | Predicted PP-loop superfamily ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Chromate resistance protein ChrB. | 0.608 |
exsB | folE | H16_A2826 | H16_B1967 | Predicted PP-loop superfamily ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | GTP cyclohydrolase I. | 0.428 |
exsB | h16_A0426 | H16_A2826 | H16_A0426 | Predicted PP-loop superfamily ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Enzyme related to GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.995 |
exsB | h16_A1925 | H16_A2826 | H16_A1925 | Predicted PP-loop superfamily ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Organic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.994 |
exsB | ptpS | H16_A2826 | H16_A1924 | Predicted PP-loop superfamily ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 6-Pyruvoyl tetrahydrobiopterin synthase protein. | 0.939 |
exsB | tpx | H16_A2826 | H16_A3175 | Predicted PP-loop superfamily ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Thiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily. | 0.674 |
folE | exsB | H16_B1967 | H16_A2826 | GTP cyclohydrolase I. | Predicted PP-loop superfamily ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.428 |
folE | h16_A0426 | H16_B1967 | H16_A0426 | GTP cyclohydrolase I. | Enzyme related to GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.539 |
folE | h16_A1925 | H16_B1967 | H16_A1925 | GTP cyclohydrolase I. | Organic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.632 |
folE | ptpS | H16_B1967 | H16_A1924 | GTP cyclohydrolase I. | 6-Pyruvoyl tetrahydrobiopterin synthase protein. | 0.984 |
guaA | h16_A0426 | H16_A2028 | H16_A0426 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Enzyme related to GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.565 |
guaA | h16_A1923 | H16_A2028 | H16_A1923 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Cytosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.679 |
guaA | h16_A1925 | H16_A2028 | H16_A1925 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Organic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.528 |
guaA | nrdA | H16_A2028 | H16_A3235 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Ribonucleoside-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.672 |
guaA | ptpS | H16_A2028 | H16_A1924 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 6-Pyruvoyl tetrahydrobiopterin synthase protein. | 0.512 |
h16_A0426 | exsB | H16_A0426 | H16_A2826 | Enzyme related to GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | Predicted PP-loop superfamily ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.995 |
h16_A0426 | folE | H16_A0426 | H16_B1967 | Enzyme related to GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | GTP cyclohydrolase I. | 0.539 |