STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
h16_A2524APC transporter, SSS family; 14 TMHs. (683 aa)    
Predicted Functional Partners:
h16_A0541
Predicted membrane protein; 2 TMHs.
 
  
 0.827
h16_B1356
Conserved hypothetical membrane spanning protein.
 
  
 0.809
h16_B1336
Conserved hypothetical membrane spanning protein.
 
  
 0.776
acoE
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. Although acetate is the preferred substrate of AcsA, propionate is also used, but at a diminished rate compared with that of acetate. Fatty acid [...]
  
  
 0.749
h16_B1662
Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase.
  
  
 0.505
h16_A1197
Acyl-CoA synthetase.
  
  
 0.494
h16_A1412
Benzoate-coenzyme A ligase.
  
  
 0.494
h16_A1616
Acetyl-coenzyme A synthetase.
  
  
 0.494
aceB
Malate synthase; Belongs to the malate synthase family.
  
  
 0.494
abmG
2-Aminobenzoate-CoA ligase.
  
  
 0.494
Your Current Organism:
Cupriavidus necator
NCBI taxonomy Id: 381666
Other names: Alcaligenes eutropha H16, C. necator H16, Cupriavidus necator ATCC 17699, Cupriavidus necator H16, Ralstonia eutropha ATCC 17699, Ralstonia eutropha H16, Ralstonia eutropha str. H16, Ralstonia eutropha strain H16, Wautersia eutropha H16
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