STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pncBNicotinic acid phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (392 aa)    
Predicted Functional Partners:
pncA
Bifunctional Pyrazinamidase/Nicotinamidase.
 
 
 0.975
nadD
Nicotinic acid mono-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
 0.943
nadC
Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family.
   
 0.933
h16_B0560
Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Belongs to the NadC/ModD family.
   
 0.933
h16_A3156
Putative competence-damage protein; Belongs to the CinA family.
  
 
 0.931
h16_A2761
NADH pyrophosphatase I of the Nudix family of hydrolases.
    
 0.926
surE
Stationary phase survival protein; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.906
h16_B0594
Predicted acid phosphatase.
    
 0.906
h16_A0920
Aerobic-type carbon monoxide dehydrogenase homolog, large subunit.
    
  0.905
h16_A0921
Aerobic-type carbon monoxide dehydrogenase homolog, small subunit.
    
  0.903
Your Current Organism:
Cupriavidus necator
NCBI taxonomy Id: 381666
Other names: Alcaligenes eutropha H16, C. necator H16, Cupriavidus necator ATCC 17699, Cupriavidus necator H16, Ralstonia eutropha ATCC 17699, Ralstonia eutropha H16, Ralstonia eutropha str. H16, Ralstonia eutropha strain H16, Wautersia eutropha H16
Server load: medium (46%) [HD]