STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
h16_A2731Uncharacterized conserved protein; Converts GTP to 7,8-dihydroneopterin triphosphate. (267 aa)    
Predicted Functional Partners:
ptpS
6-Pyruvoyl tetrahydrobiopterin synthase protein.
    
 0.928
h16_A0455
dATP pyrophosphohydrolase.
 
  
  0.922
folE
GTP cyclohydrolase I.
     
 0.919
ribBA
Bifunctional riboflavin biosynthesis protein RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
    
 0.908
h16_B0632
Two domain protein: GTP cyclohydrolase II; In the N-terminal section; belongs to the DHBP synthase family.
    
 0.908
ribA
GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.
     
 0.905
h16_A2182
Alkaline phosphatase; Belongs to the alkaline phosphatase family.
     
  0.900
h16_A2183
Alkaline phosphatase; Unknown EC_number=3.1.3.1-; Belongs to the alkaline phosphatase family.
     
  0.900
moaA1
Molybdopterin biosynthesis protein; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
    
  0.900
phoD
Phosphodiesterase/alkaline phosphatase D.
     
  0.900
Your Current Organism:
Cupriavidus necator
NCBI taxonomy Id: 381666
Other names: Alcaligenes eutropha H16, C. necator H16, Cupriavidus necator ATCC 17699, Cupriavidus necator H16, Ralstonia eutropha ATCC 17699, Ralstonia eutropha H16, Ralstonia eutropha str. H16, Ralstonia eutropha strain H16, Wautersia eutropha H16
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