STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
h16_A2747Acetaldehyde dehydrogenase (acetylating) NAD-dependent; Catalyzes the conversion of sulfoacetyl-CoA and NADPH to sulfoacetaldehyde, CoA and NADP(+). Specific for NADP(+) and sulfoacetaldehyde. (493 aa)    
Predicted Functional Partners:
h16_A2748
Long-chain-fatty-acid-CoA ligase; Catalyzes the CoA- and ATP-dependent conversion of sulfoacetate to sulfoacetyl-CoA and AMP; Belongs to the ATP-dependent AMP-binding enzyme family.
 0.978
h16_A0861
Alcohol dehydrogenase, class IV.
 
 0.970
gbd
NAD-dependent 4-hydroxybutyrate dehydrogenase.
 
 0.963
h16_B0831
Alcohol dehydrogenase, class IV.
 
 0.962
pcpE
2-Chloromaleylacetate/maleylacetate reductase.
 
 0.959
h16_A2749
MFS transporter, ACS family; May transport sulfoacetate into the cell. Belongs to the major facilitator superfamily.
  
  
 0.878
h16_A2746
Transcriptional regulator, IclR-family; May regulate transcription of the sauSTU operon.
 
   
 0.846
h16_B1024
Transporter of the major facilitator superfamily.
  
  
 0.841
h16_B1138
Transporter of the major facilitator superfamily; 11 strong transmembrane helices (TMpred).
  
  
 0.841
h16_A1786
Maleylacetate reductase.
 
 0.821
Your Current Organism:
Cupriavidus necator
NCBI taxonomy Id: 381666
Other names: Alcaligenes eutropha H16, C. necator H16, Cupriavidus necator ATCC 17699, Cupriavidus necator H16, Ralstonia eutropha ATCC 17699, Ralstonia eutropha H16, Ralstonia eutropha str. H16, Ralstonia eutropha strain H16, Wautersia eutropha H16
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