STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
h16_A2959Pantoate-beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (282 aa)    
Predicted Functional Partners:
panD
Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
 
 0.999
panB
Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
  
 0.998
h16_A0136
Transcriptional regulator, BAF-family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
  
 
 0.975
aptA
Omega-amino acid-pyruvate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.920
apbA1
Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
    
 0.919
apbA2
Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
    
 0.919
apbA3
Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
    
 0.919
cmk
Cytidylate kinase.
      0.911
dfp
Phosphopantothenoylcysteine synthetase/decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
 
 
 0.908
gabT
4-Aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
 0.908
Your Current Organism:
Cupriavidus necator
NCBI taxonomy Id: 381666
Other names: Alcaligenes eutropha H16, C. necator H16, Cupriavidus necator ATCC 17699, Cupriavidus necator H16, Ralstonia eutropha ATCC 17699, Ralstonia eutropha H16, Ralstonia eutropha str. H16, Ralstonia eutropha strain H16, Wautersia eutropha H16
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