STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
h16_A3102Glutathione peroxidase; Belongs to the glutathione peroxidase family. (164 aa)    
Predicted Functional Partners:
h16_B1097
Peroxiredoxin.
  
 0.965
h16_A3267
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
   
 0.932
lpdaA
Dihydrolipoamide dehydrogenase (E3 component of pyruvate or 2-oxoglutarate DH-complexes).
  
 0.929
gshB
Glutathione synthase; Belongs to the prokaryotic GSH synthase family.
    
 0.919
ggt2a
Gamma-glutamyltransferase 2.
    
 0.911
h16_A1098
Gamma-glutamyltransferase 1.
    
 0.911
ggt2b
Gamma-glutamyltransferase 2.
    
 0.911
ggt2c
Gamma-glutamyltransferase 2.
    
 0.911
h16_A0065
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
  
  
 
0.908
h16_A2792
Uncharacterized protein involved in cation transport; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.
    
 0.904
Your Current Organism:
Cupriavidus necator
NCBI taxonomy Id: 381666
Other names: Alcaligenes eutropha H16, C. necator H16, Cupriavidus necator ATCC 17699, Cupriavidus necator H16, Ralstonia eutropha ATCC 17699, Ralstonia eutropha H16, Ralstonia eutropha str. H16, Ralstonia eutropha strain H16, Wautersia eutropha H16
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