STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gabD3Succinate-semialdehyde dehydrogenase (NADP+); Belongs to the aldehyde dehydrogenase family. (482 aa)    
Predicted Functional Partners:
gabT
4-Aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 0.933
gbd
NAD-dependent 4-hydroxybutyrate dehydrogenase.
 
 0.930
sdhA
Succinate dehydrogenase (flavoprotein subunit); Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
  
 0.930
sdhB
Succinate dehydrogenase (Fe-S protein subunit); Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 
 0.917
hpaI1
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Belongs to the HpcH/HpaI aldolase family.
  
 
 0.912
hpaI2
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Belongs to the HpcH/HpaI aldolase family.
  
 
 0.912
h16_A1358
Acetyl-CoA hydrolase.
  
 
 0.911
sdhC
Succinate dehydrogenase (cytochrome b subunit).
  
 
 0.911
sdhD
Succinate dehydrogenase (hydrophobic anchor subunit).
   
 
 0.909
mdh1
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.837
Your Current Organism:
Cupriavidus necator
NCBI taxonomy Id: 381666
Other names: Alcaligenes eutropha H16, C. necator H16, Cupriavidus necator ATCC 17699, Cupriavidus necator H16, Ralstonia eutropha ATCC 17699, Ralstonia eutropha H16, Ralstonia eutropha str. H16, Ralstonia eutropha strain H16, Wautersia eutropha H16
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