STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
norR2Nitric oxide reductase regulator (NorR2); Required for the nitric oxide (NO) induced expression of NO reductase. Not required for expression of 2 other pathway members, nitrate reductase (nirS) and nitrous oxide reductase (nosZ). (521 aa)    
Predicted Functional Partners:
rpoN
DNA-directed RNA polymerase sigma subunit (RpoN); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
   
 0.886
norB2
Nitric oxide reductase qNor type (NorB2); 14 TMHs.
 
   
 0.822
norA2
NorA2 protein (NorA2); Di-iron-containing protein involved in the repair of iron- sulfur clusters; Belongs to the RIC family.
 
   
 0.696
cheA1
Chemotaxis protein histidine kinase.
     
 0.637
rfbF
Putative glucose-1-phosphate cytidylyltransferase.
      
 0.608
h16_A1373
Signal transduction histidine kinase containing a PAS sensor domain; 2 TMHs.
   
 
 0.555
h16_B1541
Signal transduction histidine kinase containing a receiver domain (hybrid) and PAS sensor domains; REC (residues546 to 659, 4e-19) with a complete phosphorylation pocket (DD-D55-T88-K98).
  
 
 0.532
ssuA1
ABC-type transporter, periplasmic component: TauT family.
    
 0.517
ntrC
Response regulator, nitrogen regulation protein NtrC; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.
 
 
 
0.488
h16_A0696
Predicted signal transduction protein containinga membrane domain, an EAL and a GGDEF domain.
   
 
 0.486
Your Current Organism:
Cupriavidus necator
NCBI taxonomy Id: 381666
Other names: Alcaligenes eutropha H16, C. necator H16, Cupriavidus necator ATCC 17699, Cupriavidus necator H16, Ralstonia eutropha ATCC 17699, Ralstonia eutropha H16, Ralstonia eutropha str. H16, Ralstonia eutropha strain H16, Wautersia eutropha H16
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