node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Fnod_0683 | Fnod_1292 | Fnod_0683 | Fnod_1292 | PFAM: ribonuclease H; KEGG: gfo:GFO_1824 RecD-like exodeoxyribonuclease. | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | 0.425 |
Fnod_0683 | polA | Fnod_0683 | Fnod_0360 | PFAM: ribonuclease H; KEGG: gfo:GFO_1824 RecD-like exodeoxyribonuclease. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.733 |
Fnod_0683 | polC | Fnod_0683 | Fnod_1721 | PFAM: ribonuclease H; KEGG: gfo:GFO_1824 RecD-like exodeoxyribonuclease. | DNA polymerase III, alpha subunit; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.517 |
Fnod_0683 | ruvA | Fnod_0683 | Fnod_0801 | PFAM: ribonuclease H; KEGG: gfo:GFO_1824 RecD-like exodeoxyribonuclease. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.571 |
Fnod_0683 | ruvB | Fnod_0683 | Fnod_0152 | PFAM: ribonuclease H; KEGG: gfo:GFO_1824 RecD-like exodeoxyribonuclease. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.529 |
Fnod_0683 | ruvC | Fnod_0683 | Fnod_1720 | PFAM: ribonuclease H; KEGG: gfo:GFO_1824 RecD-like exodeoxyribonuclease. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.593 |
Fnod_0683 | topA | Fnod_0683 | Fnod_1027 | PFAM: ribonuclease H; KEGG: gfo:GFO_1824 RecD-like exodeoxyribonuclease. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.957 |
Fnod_1106 | ruvA | Fnod_1106 | Fnod_0801 | PFAM: protein of unknown function DUF28; KEGG: tma:TM0466 hypothetical protein. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.400 |
Fnod_1106 | ruvB | Fnod_1106 | Fnod_0152 | PFAM: protein of unknown function DUF28; KEGG: tma:TM0466 hypothetical protein. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.442 |
Fnod_1106 | ruvC | Fnod_1106 | Fnod_1720 | PFAM: protein of unknown function DUF28; KEGG: tma:TM0466 hypothetical protein. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.495 |
Fnod_1292 | Fnod_0683 | Fnod_1292 | Fnod_0683 | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | PFAM: ribonuclease H; KEGG: gfo:GFO_1824 RecD-like exodeoxyribonuclease. | 0.425 |
Fnod_1292 | polA | Fnod_1292 | Fnod_0360 | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.647 |
Fnod_1292 | ruvA | Fnod_1292 | Fnod_0801 | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.433 |
Fnod_1292 | ruvC | Fnod_1292 | Fnod_1720 | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.627 |
Fnod_1292 | topA | Fnod_1292 | Fnod_1027 | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.548 |
polA | Fnod_0683 | Fnod_0360 | Fnod_0683 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | PFAM: ribonuclease H; KEGG: gfo:GFO_1824 RecD-like exodeoxyribonuclease. | 0.733 |
polA | Fnod_1292 | Fnod_0360 | Fnod_1292 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | 0.647 |
polA | polC | Fnod_0360 | Fnod_1721 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | DNA polymerase III, alpha subunit; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.627 |
polA | queA | Fnod_0360 | Fnod_1719 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | S-adenosylmethionine--tRNA-ribosyltransferase- isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.549 |
polA | ruvA | Fnod_0360 | Fnod_0801 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.707 |