node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Hac_0770 | panC | Hac_0770 | Hac_0259 | Putative transcriptional regulator; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.618 |
coaX | dfp | Hac_1225 | Hac_1211 | Transcriptional regulators; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | Pantothenate metabolism flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.925 |
coaX | panC | Hac_1225 | Hac_0259 | Transcriptional regulators; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.963 |
coaX | panD | Hac_1225 | Hac_0047 | Transcriptional regulators; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | Aspartate 1-decarboxylase alpha chain; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.685 |
cynT | kdsA | Hac_0257 | Hac_0256 | CynT protein; (Q9ZN54) Carbonic anhydrase (EC 4.2.1.1); High confidence in function and specificity. | 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase); (Q9ZN55) 2-dehydro-3-deoxyphosphooctonate aldolase (EC 2.5.1.55) (Phospho-2-dehydro-3-deoxyoctonate aldolase) (3-deoxy-D-manno-octulosonic acid 8-phosphate synthetase) (KDO-8-phosphate synthetase) (KDO 8-P synthase) (KDOPS); High confidence in function and specificity; Belongs to the KdsA family. | 0.820 |
cynT | nusB | Hac_0257 | Hac_0254 | CynT protein; (Q9ZN54) Carbonic anhydrase (EC 4.2.1.1); High confidence in function and specificity. | Transcription termination protein; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.815 |
cynT | panC | Hac_0257 | Hac_0259 | CynT protein; (Q9ZN54) Carbonic anhydrase (EC 4.2.1.1); High confidence in function and specificity. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.638 |
cynT | pyrF | Hac_0257 | Hac_0258 | CynT protein; (Q9ZN54) Carbonic anhydrase (EC 4.2.1.1); High confidence in function and specificity. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP). | 0.653 |
cynT | ribH | Hac_0257 | Hac_0255 | CynT protein; (Q9ZN54) Carbonic anhydrase (EC 4.2.1.1); High confidence in function and specificity. | Riboflavin synthase beta chain; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.815 |
dfp | coaX | Hac_1211 | Hac_1225 | Pantothenate metabolism flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Transcriptional regulators; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.925 |
dfp | panB | Hac_1211 | Hac_1169 | Pantothenate metabolism flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.522 |
dfp | panC | Hac_1211 | Hac_0259 | Pantothenate metabolism flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.895 |
kdsA | cynT | Hac_0256 | Hac_0257 | 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase); (Q9ZN55) 2-dehydro-3-deoxyphosphooctonate aldolase (EC 2.5.1.55) (Phospho-2-dehydro-3-deoxyoctonate aldolase) (3-deoxy-D-manno-octulosonic acid 8-phosphate synthetase) (KDO-8-phosphate synthetase) (KDO 8-P synthase) (KDOPS); High confidence in function and specificity; Belongs to the KdsA family. | CynT protein; (Q9ZN54) Carbonic anhydrase (EC 4.2.1.1); High confidence in function and specificity. | 0.820 |
kdsA | nusB | Hac_0256 | Hac_0254 | 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase); (Q9ZN55) 2-dehydro-3-deoxyphosphooctonate aldolase (EC 2.5.1.55) (Phospho-2-dehydro-3-deoxyoctonate aldolase) (3-deoxy-D-manno-octulosonic acid 8-phosphate synthetase) (KDO-8-phosphate synthetase) (KDO 8-P synthase) (KDOPS); High confidence in function and specificity; Belongs to the KdsA family. | Transcription termination protein; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.835 |
kdsA | panC | Hac_0256 | Hac_0259 | 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase); (Q9ZN55) 2-dehydro-3-deoxyphosphooctonate aldolase (EC 2.5.1.55) (Phospho-2-dehydro-3-deoxyoctonate aldolase) (3-deoxy-D-manno-octulosonic acid 8-phosphate synthetase) (KDO-8-phosphate synthetase) (KDO 8-P synthase) (KDOPS); High confidence in function and specificity; Belongs to the KdsA family. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.648 |
kdsA | pyrF | Hac_0256 | Hac_0258 | 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase); (Q9ZN55) 2-dehydro-3-deoxyphosphooctonate aldolase (EC 2.5.1.55) (Phospho-2-dehydro-3-deoxyoctonate aldolase) (3-deoxy-D-manno-octulosonic acid 8-phosphate synthetase) (KDO-8-phosphate synthetase) (KDO 8-P synthase) (KDOPS); High confidence in function and specificity; Belongs to the KdsA family. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP). | 0.648 |
kdsA | ribH | Hac_0256 | Hac_0255 | 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase); (Q9ZN55) 2-dehydro-3-deoxyphosphooctonate aldolase (EC 2.5.1.55) (Phospho-2-dehydro-3-deoxyoctonate aldolase) (3-deoxy-D-manno-octulosonic acid 8-phosphate synthetase) (KDO-8-phosphate synthetase) (KDO 8-P synthase) (KDOPS); High confidence in function and specificity; Belongs to the KdsA family. | Riboflavin synthase beta chain; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.835 |
nusB | cynT | Hac_0254 | Hac_0257 | Transcription termination protein; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | CynT protein; (Q9ZN54) Carbonic anhydrase (EC 4.2.1.1); High confidence in function and specificity. | 0.815 |
nusB | kdsA | Hac_0254 | Hac_0256 | Transcription termination protein; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase); (Q9ZN55) 2-dehydro-3-deoxyphosphooctonate aldolase (EC 2.5.1.55) (Phospho-2-dehydro-3-deoxyoctonate aldolase) (3-deoxy-D-manno-octulosonic acid 8-phosphate synthetase) (KDO-8-phosphate synthetase) (KDO 8-P synthase) (KDOPS); High confidence in function and specificity; Belongs to the KdsA family. | 0.835 |
nusB | panC | Hac_0254 | Hac_0259 | Transcription termination protein; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.645 |