STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
deoD(P56463) Purine nucleoside phosphorylase (EC 2.4.2.1) (Inosine phosphorylase) (PNP); High confidence in function and specificity. (233 aa)    
Predicted Functional Partners:
deoB
Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
  
 
 0.977
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
    
 0.932
cobT
Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphor; (O25849) NAD-dependent deacetylase (EC 3.5.1.-) (Regulatory protein SIR2 homolog); High confidence in function and specificity; Belongs to the sirtuin family. Class III subfamily.
    
 0.921
gpt
Xanthine-guanine phosphoribosyltransferase; High confidence in function and specificity.
     
  0.900
cpdB
2',3'-cyclic-nucleotide 2'-phosphodiesterase; (P44764) 23-cyclic-nucleotide 2-phosphodiesterase precursor (EC 3.1.4.16); High confidence in function and specificity; Belongs to the 5'-nucleotidase family.
    
  0.900
surE
Stationary-phase survival protein (surE); Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
  0.900
nupC
(Q62773) Sodium/nucleoside cotransporter 2 (Na(+)/nucleoside cotransporter 2) (Sodium-coupled nucleoside transporter 2) (Concentrative nucleoside transporter 2) (CNT 2) (Sodium/purine nucleoside co-transporter) (SPNT) (RCNT2); hypothetical protein; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
       0.775
punB
Purine nucleoside phosphorylase; (P51105) Dihydroflavonol-4-reductase (EC 1.1.1.219) (DFR) (Dihydrokaempferol 4-reductase); hypothetical protein.
   
 
  0.507
Hac_0525
Chlorohydrolase; Function unclear.
     
  0.499
Hac_1188
Conserved hypothetical protein.
     
  0.499
Your Current Organism:
Helicobacter acinonychis
NCBI taxonomy Id: 382638
Other names: H. acinonychis str. Sheeba, Helicobacter acinonychis Sheeba, Helicobacter acinonychis str. Sheeba, Helicobacter acinonychis strain Sheeba
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.