STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aimE-2Aliphatic amidase; Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide; Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family. (334 aa)    
Predicted Functional Partners:
gdhA
NADP-specific glutamate dehydrogenase; High confidence in function and specificity; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 
 0.928
glnA
GlnA protein; Glutamine synthetase (EC 6.3.1.2) (Glutamate--ammonia ligase); High confidence in function and specificity.
    
 0.902
fumC
Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
     
  0.800
mqo
Malate dehydrogenase (acceptor); (O24913) Malate:quinone oxidoreductase (EC 1.1.99.16) (Malate dehydrogenase [acceptor]) (MQO); High confidence in function and specificity.
     
  0.800
purU
Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).
     
  0.800
rocF
Arginase; (P39138) Arginase (EC 3.5.3.1)(P39138) Arginase (EC 3.5.3.1); High confidence in function and specificity; Belongs to the arginase family.
  
 0.675
Hac_1077
(Q9ZKR8) Hypothetical protein JHP0867; High confidence in function and specificity.
   
   0.534
queE
Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
       0.509
Hac_1078
Conserved hypothetical protein.
       0.509
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
   
 
 0.483
Your Current Organism:
Helicobacter acinonychis
NCBI taxonomy Id: 382638
Other names: H. acinonychis str. Sheeba, Helicobacter acinonychis Sheeba, Helicobacter acinonychis str. Sheeba, Helicobacter acinonychis strain Sheeba
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