node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Hac_1077 | Hac_1078 | Hac_1077 | Hac_1078 | (Q9ZKR8) Hypothetical protein JHP0867; High confidence in function and specificity. | Conserved hypothetical protein. | 0.789 |
Hac_1077 | aimE-2 | Hac_1077 | Hac_1079 | (Q9ZKR8) Hypothetical protein JHP0867; High confidence in function and specificity. | Aliphatic amidase; Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide; Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family. | 0.534 |
Hac_1077 | guaA | Hac_1077 | Hac_0466 | (Q9ZKR8) Hypothetical protein JHP0867; High confidence in function and specificity. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.502 |
Hac_1077 | queE | Hac_1077 | Hac_1076 | (Q9ZKR8) Hypothetical protein JHP0867; High confidence in function and specificity. | Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.993 |
Hac_1078 | Hac_1077 | Hac_1078 | Hac_1077 | Conserved hypothetical protein. | (Q9ZKR8) Hypothetical protein JHP0867; High confidence in function and specificity. | 0.789 |
Hac_1078 | aimE-2 | Hac_1078 | Hac_1079 | Conserved hypothetical protein. | Aliphatic amidase; Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide; Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family. | 0.509 |
Hac_1078 | queE | Hac_1078 | Hac_1076 | Conserved hypothetical protein. | Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.789 |
aimE-2 | Hac_1077 | Hac_1079 | Hac_1077 | Aliphatic amidase; Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide; Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family. | (Q9ZKR8) Hypothetical protein JHP0867; High confidence in function and specificity. | 0.534 |
aimE-2 | Hac_1078 | Hac_1079 | Hac_1078 | Aliphatic amidase; Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide; Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family. | Conserved hypothetical protein. | 0.509 |
aimE-2 | fumC | Hac_1079 | Hac_0131 | Aliphatic amidase; Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide; Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family. | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.800 |
aimE-2 | gdhA | Hac_1079 | Hac_0475 | Aliphatic amidase; Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide; Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family. | NADP-specific glutamate dehydrogenase; High confidence in function and specificity; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.928 |
aimE-2 | glnA | Hac_1079 | Hac_0878 | Aliphatic amidase; Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide; Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family. | GlnA protein; Glutamine synthetase (EC 6.3.1.2) (Glutamate--ammonia ligase); High confidence in function and specificity. | 0.902 |
aimE-2 | guaA | Hac_1079 | Hac_0466 | Aliphatic amidase; Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide; Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.483 |
aimE-2 | mqo | Hac_1079 | Hac_1519 | Aliphatic amidase; Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide; Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family. | Malate dehydrogenase (acceptor); (O24913) Malate:quinone oxidoreductase (EC 1.1.99.16) (Malate dehydrogenase [acceptor]) (MQO); High confidence in function and specificity. | 0.800 |
aimE-2 | purU | Hac_1079 | Hac_1657 | Aliphatic amidase; Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide; Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family. | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). | 0.800 |
aimE-2 | queE | Hac_1079 | Hac_1076 | Aliphatic amidase; Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide; Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family. | Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.509 |
aimE-2 | rocF | Hac_1079 | Hac_1761 | Aliphatic amidase; Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide; Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family. | Arginase; (P39138) Arginase (EC 3.5.3.1)(P39138) Arginase (EC 3.5.3.1); High confidence in function and specificity; Belongs to the arginase family. | 0.675 |
fumC | aimE-2 | Hac_0131 | Hac_1079 | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Aliphatic amidase; Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide; Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family. | 0.800 |
fumC | mqo | Hac_0131 | Hac_1519 | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Malate dehydrogenase (acceptor); (O24913) Malate:quinone oxidoreductase (EC 1.1.99.16) (Malate dehydrogenase [acceptor]) (MQO); High confidence in function and specificity. | 0.936 |
fumC | purU | Hac_0131 | Hac_1657 | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). | 0.800 |