STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemAGlutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (447 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.994
hemL
Glutamate-1-semialdehyde 21-aminomutase (EC 5.4.3.8) (GSA) (Glutamate-1-semialdehyde aminotransferase) (GSA-AT); High confidence in function and specificity.
 
 0.988
gltRS
glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
     
 0.911
hemB
(Q9ZMR8) Delta-aminolevulinic acid dehydratase (EC 4.2.1.24) (Porphobilinogen synthase) (ALAD) (ALADH); High confidence in function and specificity; Belongs to the ALAD family.
 
  
 0.855
ispB
Bifunctional short chain isoprenyl diphosphate synthase [Includes: Farnesyl pyrophosphate synthetase (EC 2.5.1.1) (FPP synthetase) (Dimethylallyltransferase); Geranyltranstransferase (EC 2.5.1.10)]; High confidence in function and specificity; Belongs to the FPP/GGPP synthase family.
  
    0.821
proS
Proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...]
       0.820
Hac_1376
Hypothetical protein predicted by Glimmer/Critica; (Q55790) Hypothetical protein slr0074; hypothetical protein.
       0.778
Hac_1377
Conserved hypothetical protein.
       0.762
Hac_1382
Conserved hypothetical protein.
       0.757
napA-2
Neutrophil-activating protein A; High confidence in function and specificity; Belongs to the Dps family.
  
  
 0.750
Your Current Organism:
Helicobacter acinonychis
NCBI taxonomy Id: 382638
Other names: H. acinonychis str. Sheeba, Helicobacter acinonychis Sheeba, Helicobacter acinonychis str. Sheeba, Helicobacter acinonychis strain Sheeba
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.