STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepAAminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (496 aa)    
Predicted Functional Partners:
ggt
Ggt protein; (P36267) Gamma-glutamyltranspeptidase precursor (EC 2.3.2.2); High confidence in function and specificity.
     
 0.917
cysK
CysK protein; (Q9ZMW6) Cysteine synthase; High confidence in function and specificity.
    
 0.823
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.821
ychF
GTP-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
       0.820
aspB-2
Aspartate aminotransferase (EC 2.6.1.1) (Transaminase A) (ASPAT); High confidence in function and specificity.
   
  0.816
metB
Cystathionine gamma-synthase; High confidence in function and specificity.
   
 
  0.801
Hac_1441
Conserved hypothetical protein; Specificity unclear.
       0.705
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
     
 0.695
Hac_1444
Conserved hypothetical protein.
       0.648
fragment-86
Conserved hypothetical protein fragment 1.
       0.648
Your Current Organism:
Helicobacter acinonychis
NCBI taxonomy Id: 382638
Other names: H. acinonychis str. Sheeba, Helicobacter acinonychis Sheeba, Helicobacter acinonychis str. Sheeba, Helicobacter acinonychis strain Sheeba
Server load: low (28%) [HD]