node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Hac_1466 | cysK | Hac_1466 | Hac_1465 | Conserved hypothetical protein. | CysK protein; (Q9ZMW6) Cysteine synthase; High confidence in function and specificity. | 0.552 |
Hac_1466 | luxS | Hac_1466 | Hac_1463 | Conserved hypothetical protein. | Autoinducer-2 production protein; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.438 |
Hac_1466 | metB | Hac_1466 | Hac_1464 | Conserved hypothetical protein. | Cystathionine gamma-synthase; High confidence in function and specificity. | 0.502 |
Hac_1516 | luxS | Hac_1516 | Hac_1463 | MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. | Autoinducer-2 production protein; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.968 |
cysK | Hac_1466 | Hac_1465 | Hac_1466 | CysK protein; (Q9ZMW6) Cysteine synthase; High confidence in function and specificity. | Conserved hypothetical protein. | 0.552 |
cysK | luxS | Hac_1465 | Hac_1463 | CysK protein; (Q9ZMW6) Cysteine synthase; High confidence in function and specificity. | Autoinducer-2 production protein; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.960 |
cysK | metB | Hac_1465 | Hac_1464 | CysK protein; (Q9ZMW6) Cysteine synthase; High confidence in function and specificity. | Cystathionine gamma-synthase; High confidence in function and specificity. | 0.997 |
cysK | msrA | Hac_1465 | Hac_1495 | CysK protein; (Q9ZMW6) Cysteine synthase; High confidence in function and specificity. | Peptide methionine sulfoxide reductase MsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.517 |
cysK | ribD | Hac_1465 | Hac_0079 | CysK protein; (Q9ZMW6) Cysteine synthase; High confidence in function and specificity. | (O24750) Riboflavin biosynthesis protein ribD [Includes: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) (Riboflavin-specific deaminase); 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193) (HTP reductase)]; High confidence in function and specificity. | 0.407 |
hom | luxS | Hac_0726 | Hac_1463 | (P56429) Homoserine dehydrogenase (EC 1.1.1.3) (HDH); High confidence in function and specificity. | Autoinducer-2 production protein; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.811 |
hom | metB | Hac_0726 | Hac_1464 | (P56429) Homoserine dehydrogenase (EC 1.1.1.3) (HDH); High confidence in function and specificity. | Cystathionine gamma-synthase; High confidence in function and specificity. | 0.910 |
hom | msrA | Hac_0726 | Hac_1495 | (P56429) Homoserine dehydrogenase (EC 1.1.1.3) (HDH); High confidence in function and specificity. | Peptide methionine sulfoxide reductase MsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.664 |
hom | thrB | Hac_0726 | Hac_1161 | (P56429) Homoserine dehydrogenase (EC 1.1.1.3) (HDH); High confidence in function and specificity. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.993 |
luxS | Hac_1466 | Hac_1463 | Hac_1466 | Autoinducer-2 production protein; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | Conserved hypothetical protein. | 0.438 |
luxS | Hac_1516 | Hac_1463 | Hac_1516 | Autoinducer-2 production protein; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. | 0.968 |
luxS | cysK | Hac_1463 | Hac_1465 | Autoinducer-2 production protein; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | CysK protein; (Q9ZMW6) Cysteine synthase; High confidence in function and specificity. | 0.960 |
luxS | hom | Hac_1463 | Hac_0726 | Autoinducer-2 production protein; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | (P56429) Homoserine dehydrogenase (EC 1.1.1.3) (HDH); High confidence in function and specificity. | 0.811 |
luxS | metB | Hac_1463 | Hac_1464 | Autoinducer-2 production protein; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | Cystathionine gamma-synthase; High confidence in function and specificity. | 0.981 |
luxS | msrA | Hac_1463 | Hac_1495 | Autoinducer-2 production protein; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | Peptide methionine sulfoxide reductase MsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.471 |
luxS | ribD | Hac_1463 | Hac_0079 | Autoinducer-2 production protein; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | (O24750) Riboflavin biosynthesis protein ribD [Includes: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) (Riboflavin-specific deaminase); 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193) (HTP reductase)]; High confidence in function and specificity. | 0.515 |