STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bioBBiotin synthetase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (282 aa)    
Predicted Functional Partners:
bioD
(Q9ZN34) Dethiobiotin synthetase (EC 6.3.3.3) (Dethiobiotin synthase) (DTB synthetase) (DTBS); High confidence in function and specificity.
 
 
 0.995
bioA
BioA protein; (Q9ZKM5) Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) (78-diamino-pelargonic acid aminotransferase) (DAPA aminotransferase); High confidence in function and specificity; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.982
bioF
8-amino-7-oxononanoate synthase; High confidence in function and specificity.
  
 0.935
birA
(P37416) BirA bifunctional protein [Includes: Biotin operon repressor; Biotin--[acetyl-CoA-carboxylase] synthetase (EC 6.3.4.15) (Biotin--protein ligase)]; High confidence in function and specificity.
  
 
 0.917
ubiE
Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).
  
  
 0.633
gltA
(Q9ZN37) Citrate synthase (EC 2.3.3.1); High confidence in function and specificity; Belongs to the citrate synthase family.
     
 0.632
rbn
tRNA processing ribonuclease BN; High confidence in function and specificity.
       0.612
flgE
(Q9ZKY0) Flagellar hook protein flgE; High confidence in function and specificity.
      
 0.593
flgE-2
(P50610) Flagellar hook protein flgE; Function unclear.
      
 0.593
xseB
Predicted exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.
  
    0.544
Your Current Organism:
Helicobacter acinonychis
NCBI taxonomy Id: 382638
Other names: H. acinonychis str. Sheeba, Helicobacter acinonychis Sheeba, Helicobacter acinonychis str. Sheeba, Helicobacter acinonychis strain Sheeba
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.