STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_2681UBA/THIF-type NAD/FAD-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (382 aa)    
Predicted Functional Partners:
SPRI_5392
Thiamine biosynthesis protein ThiS; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.950
SPRI_2673
Molybdopterin biosynthesis protein MoeE; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 0.848
thiG
Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
  
  
 0.833
SPRI_2682
ABC transporter ATP-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
    0.820
SPRI_2388
Cysteine desulfurase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
 0.770
SPRI_5342
Aminotransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the sulfur carrier protein TusA family.
   
 0.770
thiC
Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
  
  
 0.762
SPRI_5448
Peptidase S16; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
    
 0.759
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
  
 0.677
SPRI_4015
Thiamine biosynthesis protein ThiS; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.663
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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