node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rcas_0698 | Rcas_0858 | Rcas_0698 | Rcas_0858 | KEGG: rrs:RoseRS_4344 2-dehydropantoate 2-reductase; TIGRFAM: 2-dehydropantoate 2-reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; Ketopantoate reductase ApbA/PanE domain protein. | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.920 |
Rcas_0698 | panB | Rcas_0698 | Rcas_0334 | KEGG: rrs:RoseRS_4344 2-dehydropantoate 2-reductase; TIGRFAM: 2-dehydropantoate 2-reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; Ketopantoate reductase ApbA/PanE domain protein. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.924 |
Rcas_0698 | panC | Rcas_0698 | Rcas_0333 | KEGG: rrs:RoseRS_4344 2-dehydropantoate 2-reductase; TIGRFAM: 2-dehydropantoate 2-reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; Ketopantoate reductase ApbA/PanE domain protein. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.924 |
Rcas_0858 | Rcas_0698 | Rcas_0858 | Rcas_0698 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | KEGG: rrs:RoseRS_4344 2-dehydropantoate 2-reductase; TIGRFAM: 2-dehydropantoate 2-reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; Ketopantoate reductase ApbA/PanE domain protein. | 0.920 |
Rcas_0858 | panB | Rcas_0858 | Rcas_0334 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.957 |
Rcas_0858 | panC | Rcas_0858 | Rcas_0333 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.924 |
Rcas_1005 | panB | Rcas_1005 | Rcas_0334 | KEGG: rrs:RoseRS_0439 nicotinate-nucleotide pyrophosphorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.655 |
Rcas_3715 | panB | Rcas_3715 | Rcas_0334 | PFAM: NADP oxidoreductase coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: rrs:RoseRS_3227 6-phosphogluconate dehydrogenase, NAD-binding. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.749 |
Rcas_3715 | panC | Rcas_3715 | Rcas_0333 | PFAM: NADP oxidoreductase coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: rrs:RoseRS_3227 6-phosphogluconate dehydrogenase, NAD-binding. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.881 |
guaA | ilvD | Rcas_1739 | Rcas_2979 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | KEGG: rrs:RoseRS_3155 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.664 |
guaA | panB | Rcas_1739 | Rcas_0334 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.629 |
guaA | panC | Rcas_1739 | Rcas_0333 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.609 |
ilvD | guaA | Rcas_2979 | Rcas_1739 | KEGG: rrs:RoseRS_3155 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.664 |
ilvD | ilvE | Rcas_2979 | Rcas_1550 | KEGG: rrs:RoseRS_3155 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.985 |
ilvD | ilvE-2 | Rcas_2979 | Rcas_2479 | KEGG: rrs:RoseRS_3155 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.985 |
ilvD | panB | Rcas_2979 | Rcas_0334 | KEGG: rrs:RoseRS_3155 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.925 |
ilvE | ilvD | Rcas_1550 | Rcas_2979 | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | KEGG: rrs:RoseRS_3155 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.985 |
ilvE | ilvE-2 | Rcas_1550 | Rcas_2479 | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.912 |
ilvE | panB | Rcas_1550 | Rcas_0334 | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.920 |
ilvE-2 | ilvD | Rcas_2479 | Rcas_2979 | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | KEGG: rrs:RoseRS_3155 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.985 |