STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadKATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (278 aa)    
Predicted Functional Partners:
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
 
 0.952
nadE-2
NAD synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
 0.947
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.
    
 0.924
cobB
PFAM: Silent information regulator protein Sir2; KEGG: rrs:RoseRS_1260 silent information regulator protein Sir2; Belongs to the sirtuin family. Class III subfamily.
  
 
 0.919
Rcas_1594
PFAM: Silent information regulator protein Sir2; KEGG: rrs:RoseRS_1261 silent information regulator protein Sir2.
  
 
 0.919
Rcas_1616
PFAM: NUDIX hydrolase; KEGG: rrs:RoseRS_1329 NUDIX hydrolase.
 
 
  0.919
Rcas_4163
PFAM: Silent information regulator protein Sir2; KEGG: rrs:RoseRS_3344 silent information regulator protein Sir2.
  
 
 0.919
Rcas_0361
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
  
 0.846
Rcas_0933
PFAM: metalloenzyme domain protein; KEGG: rrs:RoseRS_4288 metalloenzyme domain protein.
       0.790
Rcas_0556
TIGRFAM: hemolysin A; PFAM: ribosomal RNA methyltransferase RrmJ/FtsJ; RNA-binding S4 domain protein; KEGG: rrs:RoseRS_3862 hemolysin A.
  
  
 0.623
Your Current Organism:
Roseiflexus castenholzii
NCBI taxonomy Id: 383372
Other names: R. castenholzii DSM 13941, Roseiflexus castenholzii DSM 13941, Roseiflexus castenholzii HLO8, Roseiflexus castenholzii str. DSM 13941, Roseiflexus castenholzii strain DSM 13941
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