STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
truAtRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (270 aa)    
Predicted Functional Partners:
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
  
 0.979
Rcas_3998
PFAM: ribosomal protein L17; KEGG: rrs:RoseRS_1157 ribosomal protein L17; Belongs to the bacterial ribosomal protein bL17 family.
  
  
 0.975
Rcas_1187
PFAM: beta-lactamase domain protein; SMART: Rhodanese domain protein; KEGG: rrs:RoseRS_0816 beta-lactamase domain protein.
   
 
 0.893
Rcas_3632
PFAM: beta-lactamase domain protein; SMART: Rhodanese domain protein; KEGG: rrs:RoseRS_3957 beta-lactamase domain protein.
   
 
 0.893
rplM
Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
  
 0.882
rpsI
PFAM: ribosomal protein S9; KEGG: rrs:RoseRS_1154 ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
  
  
 0.840
Rcas_0317
PFAM: thiamineS protein; KEGG: rrs:RoseRS_0722 thiamineS protein.
  
 
 0.834
Rcas_0318
PFAM: UBA/THIF-type NAD/FAD binding protein; Rhodanese domain protein; MoeZ/MoeB domain protein; KEGG: rrs:RoseRS_0723 UBA/ThiF-type NAD/FAD binding protein.
  
 
 0.831
rsmH
S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
   
 
 0.811
ybeY
Protein of unknown function UPF0054; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
  
   0.809
Your Current Organism:
Roseiflexus castenholzii
NCBI taxonomy Id: 383372
Other names: R. castenholzii DSM 13941, Roseiflexus castenholzii DSM 13941, Roseiflexus castenholzii HLO8, Roseiflexus castenholzii str. DSM 13941, Roseiflexus castenholzii strain DSM 13941
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.