node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Pisl_0279 | argF | Pisl_0279 | Pisl_1807 | PFAM: argininosuccinate synthase; KEGG: pai:PAE2884 argininosuccinate synthase. | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | 0.996 |
Pisl_0279 | argH | Pisl_0279 | Pisl_0281 | PFAM: argininosuccinate synthase; KEGG: pai:PAE2884 argininosuccinate synthase. | PFAM: fumarate lyase; KEGG: pai:PAE2887 argininosuccinate lyase. | 0.999 |
Pisl_0279 | carB | Pisl_0279 | Pisl_1184 | PFAM: argininosuccinate synthase; KEGG: pai:PAE2884 argininosuccinate synthase. | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; protein of unknown function DUF201; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain, oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: pai:PAE0947 carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | 0.998 |
Pisl_0279 | lysJ | Pisl_0279 | Pisl_1923 | PFAM: argininosuccinate synthase; KEGG: pai:PAE2884 argininosuccinate synthase. | N2-acetyl-L-lysine aminotransferase apoenzyme / acetylornithine aminotransferase apoenzyme; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily. | 0.968 |
Pisl_0279 | lysY | Pisl_0279 | Pisl_0276 | PFAM: argininosuccinate synthase; KEGG: pai:PAE2884 argininosuccinate synthase. | N-acetyl-gamma-glutamyl-phosphate reductase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily. | 0.988 |
Pisl_0279 | lysZ | Pisl_0279 | Pisl_0277 | PFAM: argininosuccinate synthase; KEGG: pai:PAE2884 argininosuccinate synthase. | N-acetylglutamate kinase; Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis); Belongs to the acetylglutamate kinase family. LysZ subfamily. | 0.988 |
Pisl_0951 | Pisl_1692 | Pisl_0951 | Pisl_1692 | Fumarase beta subunit; KEGG: pai:PAE2131 fumarate hydratase class I beta subunit; TIGRFAM: hydro-lyases, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyases tartrate/fumarate beta region. | KEGG: pai:PAE1689 citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase. | 0.928 |
Pisl_0951 | argH | Pisl_0951 | Pisl_0281 | Fumarase beta subunit; KEGG: pai:PAE2131 fumarate hydratase class I beta subunit; TIGRFAM: hydro-lyases, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyases tartrate/fumarate beta region. | PFAM: fumarate lyase; KEGG: pai:PAE2887 argininosuccinate lyase. | 0.847 |
Pisl_0951 | mdh | Pisl_0951 | Pisl_0612 | Fumarase beta subunit; KEGG: pai:PAE2131 fumarate hydratase class I beta subunit; TIGRFAM: hydro-lyases, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyases tartrate/fumarate beta region. | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Exhibits higher specific activity for oxaloacetate reduction than for malate oxidation in vitro. Has a strong preference for NAD. Can use NADPH for oxaloacetate reduction, but activity decreases more than 90%. No activity detected with NADP(+) and malate. Belongs to the LDH/MDH superfamily. | 0.982 |
Pisl_1197 | Pisl_1692 | Pisl_1197 | Pisl_1692 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: pai:PAE0972 adenylosuccinate lyase. | KEGG: pai:PAE1689 citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase. | 0.801 |
Pisl_1197 | argH | Pisl_1197 | Pisl_0281 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: pai:PAE0972 adenylosuccinate lyase. | PFAM: fumarate lyase; KEGG: pai:PAE2887 argininosuccinate lyase. | 0.927 |
Pisl_1197 | carB | Pisl_1197 | Pisl_1184 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: pai:PAE0972 adenylosuccinate lyase. | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; protein of unknown function DUF201; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain, oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: pai:PAE0947 carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | 0.430 |
Pisl_1197 | mdh | Pisl_1197 | Pisl_0612 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: pai:PAE0972 adenylosuccinate lyase. | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Exhibits higher specific activity for oxaloacetate reduction than for malate oxidation in vitro. Has a strong preference for NAD. Can use NADPH for oxaloacetate reduction, but activity decreases more than 90%. No activity detected with NADP(+) and malate. Belongs to the LDH/MDH superfamily. | 0.868 |
Pisl_1692 | Pisl_0951 | Pisl_1692 | Pisl_0951 | KEGG: pai:PAE1689 citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase. | Fumarase beta subunit; KEGG: pai:PAE2131 fumarate hydratase class I beta subunit; TIGRFAM: hydro-lyases, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyases tartrate/fumarate beta region. | 0.928 |
Pisl_1692 | Pisl_1197 | Pisl_1692 | Pisl_1197 | KEGG: pai:PAE1689 citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase. | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: pai:PAE0972 adenylosuccinate lyase. | 0.801 |
Pisl_1692 | argH | Pisl_1692 | Pisl_0281 | KEGG: pai:PAE1689 citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase. | PFAM: fumarate lyase; KEGG: pai:PAE2887 argininosuccinate lyase. | 0.848 |
Pisl_1692 | lysJ | Pisl_1692 | Pisl_1923 | KEGG: pai:PAE1689 citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase. | N2-acetyl-L-lysine aminotransferase apoenzyme / acetylornithine aminotransferase apoenzyme; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily. | 0.609 |
Pisl_1692 | lysY | Pisl_1692 | Pisl_0276 | KEGG: pai:PAE1689 citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase. | N-acetyl-gamma-glutamyl-phosphate reductase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily. | 0.422 |
Pisl_1692 | mdh | Pisl_1692 | Pisl_0612 | KEGG: pai:PAE1689 citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase. | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Exhibits higher specific activity for oxaloacetate reduction than for malate oxidation in vitro. Has a strong preference for NAD. Can use NADPH for oxaloacetate reduction, but activity decreases more than 90%. No activity detected with NADP(+) and malate. Belongs to the LDH/MDH superfamily. | 0.997 |
argF | Pisl_0279 | Pisl_1807 | Pisl_0279 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | PFAM: argininosuccinate synthase; KEGG: pai:PAE2884 argininosuccinate synthase. | 0.996 |