STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
carSProtein of unknown function DUF46; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. (164 aa)    
Predicted Functional Partners:
Pisl_1733
PFAM: UbiA prenyltransferase; KEGG: pai:PAE1784 hypothetical 4-hydroxybenzoate octaprenyltransferase.
 
  
 0.955
Pisl_0709
PFAM: zinc finger, C2H2-type domain protein; KEGG: pai:PAE0659 hypothetical protein containing 3 C2H2 zinc finger motifs.
       0.833
rnhB
RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
   
    0.806
Pisl_0707
PFAM: Vacuolar H+-transporting two-sector ATPase, F subunit; KEGG: pai:PAE0661 H+-transporting ATP synthase subunit F (atpF).
  
    0.715
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
   
 0.696
atpE
H+-transporting two-sector ATPase, E subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane.
  
    0.629
atpA
Sodium-transporting two-sector ATPase; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family.
  
    0.627
Pisl_1076
Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: pai:PAE0783 conserved helix-turn-helix protein.
  
     0.606
dnaG
TOPRIM domain protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
  
     0.603
Pisl_0710
KEGG: pai:PAE0658 hypothetical protein.
       0.591
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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