STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfdBPrefoldin, beta subunit; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. (125 aa)    
Predicted Functional Partners:
pfdA
Prefoldin, alpha subunit; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
  
 0.999
Pisl_0441
PFAM: DNA-binding TFAR19-related protein; KEGG: pai:PAE3044 conserved hypothetical protein; Belongs to the PDCD5 family.
 
   0.900
Pisl_0829
PFAM: phosphoesterase, RecJ domain protein; phosphoesterase, DHHA1; KEGG: pai:PAE2197 predicted phosphoesterase.
 
     0.859
Pisl_0838
PFAM: Shwachman-Bodian-Diamond syndrome proteins; KEGG: pai:PAE2209 hypothetical protein.
 
    0.857
rpoP
DNA-directed RNA polymerase, subunit P; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family.
  
  
 0.855
rpl37ae
PFAM: ribosomal L37ae protein; KEGG: pai:PAE2202 ribosomal protein L37.
 
    0.805
Pisl_0833
Ribosomal biogenesis protein, containing Brix domain; Probably involved in the biogenesis of the ribosome.
  
    0.803
Pisl_0830
KEGG: pai:PAE2198 hypothetical protein.
       0.801
Pisl_0832
KEGG: pai:PAE2200 hypothetical protein.
  
    0.790
Pisl_0958
TIGRFAM: thermosome; PFAM: chaperonin Cpn60/TCP-1; KEGG: pai:PAE2117 thermosome (chaperonin) alpha subunit.
  
 
 
 0.737
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.