node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Pisl_0301 | Pisl_0816 | Pisl_0301 | Pisl_0816 | PFAM: metallophosphoesterase; KEGG: pai:PAE2904 exonuclease SbcD, conjectural. | PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B; KEGG: pai:PAE2180 DNA-directed DNA polymerase (B1). | 0.481 |
Pisl_0301 | Pisl_0961 | Pisl_0301 | Pisl_0961 | PFAM: metallophosphoesterase; KEGG: pai:PAE2904 exonuclease SbcD, conjectural. | KEGG: pai:PAE2109 DNA-directed DNA polymerase (B3); TIGRFAM: DNA polymerase Pol2; PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B. | 0.481 |
Pisl_0301 | Pisl_0973 | Pisl_0301 | Pisl_0973 | PFAM: metallophosphoesterase; KEGG: pai:PAE2904 exonuclease SbcD, conjectural. | KEGG: pai:PAE3418 putative mRNA 3-end processing factor. | 0.576 |
Pisl_0301 | fen | Pisl_0301 | Pisl_0681 | PFAM: metallophosphoesterase; KEGG: pai:PAE2904 exonuclease SbcD, conjectural. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. A [...] | 0.969 |
Pisl_0301 | lig | Pisl_0301 | Pisl_1115 | PFAM: metallophosphoesterase; KEGG: pai:PAE2904 exonuclease SbcD, conjectural. | DNA ligase I, ATP-dependent Dnl1; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. | 0.797 |
Pisl_0301 | rfcL | Pisl_0301 | Pisl_0657 | PFAM: metallophosphoesterase; KEGG: pai:PAE2904 exonuclease SbcD, conjectural. | Replication factor C large subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. | 0.491 |
Pisl_0301 | rfcS1 | Pisl_0301 | Pisl_0656 | PFAM: metallophosphoesterase; KEGG: pai:PAE2904 exonuclease SbcD, conjectural. | Replication factor C small subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcS subfamily. | 0.491 |
Pisl_0301 | rfcS2 | Pisl_0301 | Pisl_1668 | PFAM: metallophosphoesterase; KEGG: pai:PAE2904 exonuclease SbcD, conjectural. | Replication factor C small subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcS subfamily. | 0.491 |
Pisl_0816 | Pisl_0301 | Pisl_0816 | Pisl_0301 | PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B; KEGG: pai:PAE2180 DNA-directed DNA polymerase (B1). | PFAM: metallophosphoesterase; KEGG: pai:PAE2904 exonuclease SbcD, conjectural. | 0.481 |
Pisl_0816 | Pisl_0961 | Pisl_0816 | Pisl_0961 | PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B; KEGG: pai:PAE2180 DNA-directed DNA polymerase (B1). | KEGG: pai:PAE2109 DNA-directed DNA polymerase (B3); TIGRFAM: DNA polymerase Pol2; PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B. | 0.931 |
Pisl_0816 | fen | Pisl_0816 | Pisl_0681 | PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B; KEGG: pai:PAE2180 DNA-directed DNA polymerase (B1). | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. A [...] | 0.937 |
Pisl_0816 | lig | Pisl_0816 | Pisl_1115 | PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B; KEGG: pai:PAE2180 DNA-directed DNA polymerase (B1). | DNA ligase I, ATP-dependent Dnl1; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. | 0.828 |
Pisl_0816 | pcn | Pisl_0816 | Pisl_0438 | PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B; KEGG: pai:PAE2180 DNA-directed DNA polymerase (B1). | Monomeric archaeal DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. | 0.950 |
Pisl_0816 | pcn-2 | Pisl_0816 | Pisl_0667 | PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B; KEGG: pai:PAE2180 DNA-directed DNA polymerase (B1). | Proliferating-cell nuclear antigen-like protein; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family. | 0.947 |
Pisl_0816 | rfcL | Pisl_0816 | Pisl_0657 | PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B; KEGG: pai:PAE2180 DNA-directed DNA polymerase (B1). | Replication factor C large subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. | 0.771 |
Pisl_0816 | rfcS1 | Pisl_0816 | Pisl_0656 | PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B; KEGG: pai:PAE2180 DNA-directed DNA polymerase (B1). | Replication factor C small subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcS subfamily. | 0.760 |
Pisl_0816 | rfcS2 | Pisl_0816 | Pisl_1668 | PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B; KEGG: pai:PAE2180 DNA-directed DNA polymerase (B1). | Replication factor C small subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcS subfamily. | 0.760 |
Pisl_0961 | Pisl_0301 | Pisl_0961 | Pisl_0301 | KEGG: pai:PAE2109 DNA-directed DNA polymerase (B3); TIGRFAM: DNA polymerase Pol2; PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B. | PFAM: metallophosphoesterase; KEGG: pai:PAE2904 exonuclease SbcD, conjectural. | 0.481 |
Pisl_0961 | Pisl_0816 | Pisl_0961 | Pisl_0816 | KEGG: pai:PAE2109 DNA-directed DNA polymerase (B3); TIGRFAM: DNA polymerase Pol2; PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B. | PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B; KEGG: pai:PAE2180 DNA-directed DNA polymerase (B1). | 0.931 |
Pisl_0961 | fen | Pisl_0961 | Pisl_0681 | KEGG: pai:PAE2109 DNA-directed DNA polymerase (B3); TIGRFAM: DNA polymerase Pol2; PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. A [...] | 0.950 |