STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
truBtRNA pseudouridine synthase B; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. (328 aa)    
Predicted Functional Partners:
nop10
Nucleolar RNA-binding protein Nop10p; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.
   
 0.999
Pisl_0574
snoRNP protein GAR1; KEGG: pai:PAE3330 hypothetical protein; involved in rRNA processing.
   
 0.999
rpl7ae
LSU ribosomal protein L7AE; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
 
 0.999
Pisl_0402
rRNA biogenesis protein Nop56/Nop58; PFAM: Pre-mRNA processing ribonucleoprotein, binding region; NOSIC; KEGG: pai:PAE3232 nop family pre-rRNA processing protein.
 
 
 0.994
infB
Translation initiation factor eaIF-5B; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.
 
 
 0.985
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
  
 0.980
rps15
PFAM: ribosomal protein S15; Ribosomal S13S15-like; KEGG: pai:PAE3485 ribosomal protein S13.
 
 
 0.942
Pisl_0772
KEGG: pai:PAE3473 hypothetical protein.
   
 
 0.936
cmk
TIGRFAM: cytidylate kinase, putative; KEGG: pai:PAE3225 cytidylate kinase (cmk).
      0.926
tmcA
tRNA(Met)-cytidine N(4)-acetyltransferase; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
  
 
 0.920
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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