node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Pisl_0103 | Pisl_0106 | Pisl_0103 | Pisl_0106 | PFAM: formyl transferase domain protein; KEGG: pai:PAE0219 phosphoribosylglycinamide formyltransferase. | Phosphoribosylamine--glycine ligase; KEGG: pai:PAE0216 phosphoribosylglycinamide synthetase (GARS) (purD); TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase. | 0.999 |
Pisl_0103 | Pisl_0110 | Pisl_0103 | Pisl_0110 | PFAM: formyl transferase domain protein; KEGG: pai:PAE0219 phosphoribosylglycinamide formyltransferase. | Phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: pai:PAE0221 phosphoribosylformylglycinamidine cyclo-ligase (AIRS) (purM). | 0.999 |
Pisl_0103 | Pisl_1197 | Pisl_0103 | Pisl_1197 | PFAM: formyl transferase domain protein; KEGG: pai:PAE0219 phosphoribosylglycinamide formyltransferase. | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: pai:PAE0972 adenylosuccinate lyase. | 0.972 |
Pisl_0103 | Pisl_1854 | Pisl_0103 | Pisl_1854 | PFAM: formyl transferase domain protein; KEGG: pai:PAE0219 phosphoribosylglycinamide formyltransferase. | PFAM: phosphoribosyltransferase; KEGG: pai:PAE2071 adenine phosphoribosyltransferase. | 0.667 |
Pisl_0103 | purA | Pisl_0103 | Pisl_1196 | PFAM: formyl transferase domain protein; KEGG: pai:PAE0219 phosphoribosylglycinamide formyltransferase. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.751 |
Pisl_0103 | purC | Pisl_0103 | Pisl_0105 | PFAM: formyl transferase domain protein; KEGG: pai:PAE0219 phosphoribosylglycinamide formyltransferase. | PFAM: SAICAR synthetase; KEGG: pai:PAE0215 phosphoribosylaminoimidazole-succinocarboxamide synthase (purC). | 0.992 |
Pisl_0103 | purE | Pisl_0103 | Pisl_0100 | PFAM: formyl transferase domain protein; KEGG: pai:PAE0219 phosphoribosylglycinamide formyltransferase. | 5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.992 |
Pisl_0103 | purK | Pisl_0103 | Pisl_0099 | PFAM: formyl transferase domain protein; KEGG: pai:PAE0219 phosphoribosylglycinamide formyltransferase. | 5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR); Belongs to the PurK/PurT family. | 0.987 |
Pisl_0103 | purL | Pisl_0103 | Pisl_0101 | PFAM: formyl transferase domain protein; KEGG: pai:PAE0219 phosphoribosylglycinamide formyltransferase. | Phosphoribosylformylglycinamidine synthase subunit II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] | 0.999 |
Pisl_0103 | purQ | Pisl_0103 | Pisl_0108 | PFAM: formyl transferase domain protein; KEGG: pai:PAE0219 phosphoribosylglycinamide formyltransferase. | Phosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] | 0.998 |
Pisl_0106 | Pisl_0103 | Pisl_0106 | Pisl_0103 | Phosphoribosylamine--glycine ligase; KEGG: pai:PAE0216 phosphoribosylglycinamide synthetase (GARS) (purD); TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase. | PFAM: formyl transferase domain protein; KEGG: pai:PAE0219 phosphoribosylglycinamide formyltransferase. | 0.999 |
Pisl_0106 | Pisl_0110 | Pisl_0106 | Pisl_0110 | Phosphoribosylamine--glycine ligase; KEGG: pai:PAE0216 phosphoribosylglycinamide synthetase (GARS) (purD); TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase. | Phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: pai:PAE0221 phosphoribosylformylglycinamidine cyclo-ligase (AIRS) (purM). | 0.999 |
Pisl_0106 | Pisl_1197 | Pisl_0106 | Pisl_1197 | Phosphoribosylamine--glycine ligase; KEGG: pai:PAE0216 phosphoribosylglycinamide synthetase (GARS) (purD); TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase. | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: pai:PAE0972 adenylosuccinate lyase. | 0.983 |
Pisl_0106 | Pisl_1854 | Pisl_0106 | Pisl_1854 | Phosphoribosylamine--glycine ligase; KEGG: pai:PAE0216 phosphoribosylglycinamide synthetase (GARS) (purD); TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase. | PFAM: phosphoribosyltransferase; KEGG: pai:PAE2071 adenine phosphoribosyltransferase. | 0.655 |
Pisl_0106 | purA | Pisl_0106 | Pisl_1196 | Phosphoribosylamine--glycine ligase; KEGG: pai:PAE0216 phosphoribosylglycinamide synthetase (GARS) (purD); TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.914 |
Pisl_0106 | purC | Pisl_0106 | Pisl_0105 | Phosphoribosylamine--glycine ligase; KEGG: pai:PAE0216 phosphoribosylglycinamide synthetase (GARS) (purD); TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase. | PFAM: SAICAR synthetase; KEGG: pai:PAE0215 phosphoribosylaminoimidazole-succinocarboxamide synthase (purC). | 0.996 |
Pisl_0106 | purE | Pisl_0106 | Pisl_0100 | Phosphoribosylamine--glycine ligase; KEGG: pai:PAE0216 phosphoribosylglycinamide synthetase (GARS) (purD); TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase. | 5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.998 |
Pisl_0106 | purK | Pisl_0106 | Pisl_0099 | Phosphoribosylamine--glycine ligase; KEGG: pai:PAE0216 phosphoribosylglycinamide synthetase (GARS) (purD); TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase. | 5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR); Belongs to the PurK/PurT family. | 0.981 |
Pisl_0106 | purL | Pisl_0106 | Pisl_0101 | Phosphoribosylamine--glycine ligase; KEGG: pai:PAE0216 phosphoribosylglycinamide synthetase (GARS) (purD); TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase. | Phosphoribosylformylglycinamidine synthase subunit II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] | 0.990 |
Pisl_0106 | purQ | Pisl_0106 | Pisl_0108 | Phosphoribosylamine--glycine ligase; KEGG: pai:PAE0216 phosphoribosylglycinamide synthetase (GARS) (purD); TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase. | Phosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] | 0.996 |