STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pisl_1339KEGG: pai:PAE1272 trehalose-6-phosphate synthase; TIGRFAM: HAD-superfamily hydrolase, subfamily IIB; alpha,alpha-trehalose-phosphate synthase [UDP-forming]; PFAM: glycosyl transferase, group 1; glycosyl transferase, family 20; trehalose-phosphatase; sucrose-6F-phosphate phosphohydrolase; Haloacid dehalogenase domain protein hydrolase, type 3. (737 aa)    
Predicted Functional Partners:
Pisl_1503
UDP-glucose pyrophosphorylase; PFAM: Nucleotidyl transferase; KEGG: sso:SSO0813 UTP-glucose-1-phosphate uridylyltransferase.
    
 0.929
Pisl_1967
PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain; KEGG: pai:PAE0318 hypothetical protein.
  
  
 0.577
Pisl_1338
PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: pai:PAE1165 hypothetical protein.
       0.572
Pisl_0788
SPP-like hydrolase; Catalyzes the dephosphorylation of 2-phosphoglycolate.
     
 0.408
Pisl_0904
TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: pai:PAE3068 phosphoglycolate phosphatase (pgp), conjectural.
     
 0.405
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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