STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pisl_1658PFAM: Protein of unknown function DUF54; KEGG: pai:PAE1632 conserved hypothetical protein; Belongs to the UPF0201 family. (143 aa)    
Predicted Functional Partners:
Pisl_1657
KEGG: pai:PAE1629 adenylate kinase, conjectural.
 
    0.883
trm1
N(2),N(2)-dimethylguanosine tRNA methyltransferase; Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
       0.744
Pisl_1655
Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: pai:PAE1627 putative transcriptional regulator.
       0.733
Pisl_1364
Pantothenate kinase; KEGG: pai:PAE3407 hypothetical protein.
  
     0.628
Pisl_1654
PFAM: PUA domain containing protein; KEGG: pai:PAE1626 PUA domain protein.
 
     0.617
Pisl_1361
Pantothenate synthetase; PFAM: Protein of unknown function DUF137; KEGG: pai:PAE3406 hypothetical protein.
 
   
 0.567
Pisl_0508
KEGG: pai:PAE3262 hypothetical protein.
  
     0.556
Pisl_0095
PFAM: Protein of unknown function DUF1297; Protein of unknown function DUF1246; KEGG: pai:PAE0604 hypothetical protein.
  
   
 0.555
purP
Protein of unknown function DUF1297; Catalyzes the ATP- and formate-dependent formylation of 5- aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates. Belongs to the phosphohexose mutase family.
  
   
 0.535
Pisl_0842
PFAM: Protein of unknown function DUF54; KEGG: pai:PAE2213 hypothetical protein.
  
   
 0.534
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.