STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pisl_1743PFAM: aminotransferase class-III; KEGG: pai:PAE1799 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (447 aa)    
Predicted Functional Partners:
panD
Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
    
 0.919
Pisl_1361
Pantothenate synthetase; PFAM: Protein of unknown function DUF137; KEGG: pai:PAE3406 hypothetical protein.
     
  0.900
Pisl_0249
Succinate-semialdehyde dehydrogenase (NAD(P)(+)); PFAM: aldehyde dehydrogenase; KEGG: sto:ST0064 glyceraldehyde-3-phosphate dehydrogenase, NADP dependent.
 
 
 0.795
Pisl_0567
Phosphoserine aminotransferase apoenzyme / L-aspartate aminotransferase apoenzyme; PFAM: aminotransferase, class V; aminotransferase, class I and II; KEGG: pai:PAE3321 aminotransferase (class 5).
  
 
 0.727
Pisl_1949
PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ape:APE1245 alcohol dehydrogenase.
 
 
 0.595
Pisl_1396
PFAM: Cupin 2, conserved barrel domain protein; KEGG: pai:PAE2796 hypothetical protein.
  
  
 0.585
Pisl_0273
PFAM: aspartate/glutamate/uridylate kinase; KEGG: pai:PAE2877 aspartate kinase.
     
 0.567
Pisl_0897
Agmatinase; TIGRFAM: putative agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: pai:PAE2260 agmatinase; Belongs to the arginase family.
 
  
 0.565
argF
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
  
 0.565
Pisl_1028
2-aminoadipate aminotransferase apoenzyme; PFAM: aminotransferase, class I and II; KEGG: pai:PAE2315 aminotransferase, class I.
 
  
 0.560
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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