STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cyoEProtoheme IX farnesyltransferase (heme O biosynthesis); Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (295 aa)    
Predicted Functional Partners:
cyoA
Cytochrome o ubiquinol oxidase subunit II; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.984
cyoC
Cytochrome o ubiquinol oxidase subunit III; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.983
cyoD
Cytochrome o ubiquinol oxidase, subunit IV; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.982
cyoB
Cytochrome o ubiquinol oxidase subunit I; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the heme-copper respiratory oxidase family.
 
 
 0.981
PSEEN0058
Putative cytochrome c oxidase assembly protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; factor.
  
 0.977
PSEEN0063
Putative cytochrome oxidase assembly protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; membrane component.
  
 0.974
hemH
Ferrochelatase (Protoheme ferro-lyase); Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
   
 
 0.919
cyoE1
Putative protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
  
  
 
0.918
coxA
Cytochrome c oxidase, subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
 
 
 0.906
PSEEN1837
Putative heme oxygenase BphO; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
     
  0.900
Your Current Organism:
Pseudomonas entomophila
NCBI taxonomy Id: 384676
Other names: P. entomophila L48, Pseudomonas entomophila L48, Pseudomonas entomophila str. L48, Pseudomonas entomophila strain L48
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