STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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nadKPutative inorganic polyphosphate/ATP-NAD kinase NadK; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (296 aa)    
Predicted Functional Partners:
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
 0.945
nadE
NAD synthetase, prefers NH3 over glutamine; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
    
 0.943
cobB-2
Putative NAD-dependent deacetylase 1 (Regulatory protein SIR2 homolog); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the sirtuin family. Class III subfamily.
  
 
 0.928
pntAB
Pyridine proton-translocating NAD(P) transhydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
 0.919
pntAA
Proton-translocating NAD(P) transhydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
 0.917
pntB
Pyridine nucleotide transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
     
 0.909
sthA
Soluble pyridine nucleotide transhydrogenase (NAD(P)(+) transhydrogenase [B-specific]); Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
     
 0.909
PSEEN1365
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
     
 0.905
nudC
Putative NTP pyrophosphohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
     
 0.905
PSEEN1709
Putative serine/threonine protein phosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
       0.805
Your Current Organism:
Pseudomonas entomophila
NCBI taxonomy Id: 384676
Other names: P. entomophila L48, Pseudomonas entomophila L48, Pseudomonas entomophila str. L48, Pseudomonas entomophila strain L48
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