STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rraARegulator of ribonuclease activity A; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity). (163 aa)    
Predicted Functional Partners:
PSEEN1745
Putative metal ion transporter CmaX protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; transporter.
     
 0.718
aceA
Isocitrate lyase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.688
PSEEN1743
Putative hydrolase, alpha/beta fold family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
 
     0.560
PSEEN1748
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
     
 0.559
PSEEN1747
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.516
hpaH
2-oxo-hepta-3-ene-1,7-dioic acid hydratase (OHED hydratase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
   
 0.450
sigX
RNA polymerase sigma factor; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the sigma-70 factor family. ECF subfamily.
     
 0.433
PSEEN1906
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
 
   
 0.430
ppsA
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
     
 0.419
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
 
     0.415
Your Current Organism:
Pseudomonas entomophila
NCBI taxonomy Id: 384676
Other names: P. entomophila L48, Pseudomonas entomophila L48, Pseudomonas entomophila str. L48, Pseudomonas entomophila strain L48
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