node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PSEEN4821 | dacC | PSEEN4821 | PSEEN4822 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0250 family. | D-ala-D-ala-carboxypeptidase; Function of strongly homologous gene; enzyme; Belongs to the peptidase S11 family. | 0.708 |
PSEEN4821 | lipA | PSEEN4821 | PSEEN4819 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0250 family. | Lipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.850 |
PSEEN4821 | lipB | PSEEN4821 | PSEEN4820 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0250 family. | Lipoyl(octanyl)-acyl carrier protein: protein transferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.891 |
bkdB | gcvH-1 | PSEEN3855 | PSEEN5308 | 2-oxoisovalerate dehydrogenase, lipoamide acyltransferase component; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.644 |
bkdB | gcvH-2 | PSEEN3855 | PSEEN4435 | 2-oxoisovalerate dehydrogenase, lipoamide acyltransferase component; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.636 |
bkdB | lipA | PSEEN3855 | PSEEN4819 | 2-oxoisovalerate dehydrogenase, lipoamide acyltransferase component; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Lipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.616 |
bkdB | lipB | PSEEN3855 | PSEEN4820 | 2-oxoisovalerate dehydrogenase, lipoamide acyltransferase component; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Lipoyl(octanyl)-acyl carrier protein: protein transferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.539 |
bkdB | lpd3 | PSEEN3855 | PSEEN5519 | 2-oxoisovalerate dehydrogenase, lipoamide acyltransferase component; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Dihydrolipoamide dehydrogenase 3; Function of strongly homologous gene; enzyme. | 0.993 |
bkdB | lpdV | PSEEN3855 | PSEEN3856 | 2-oxoisovalerate dehydrogenase, lipoamide acyltransferase component; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 2-oxoisovalerate dehydrogenase, lipoamide dehydrogenase component; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.998 |
dacC | PSEEN4821 | PSEEN4822 | PSEEN4821 | D-ala-D-ala-carboxypeptidase; Function of strongly homologous gene; enzyme; Belongs to the peptidase S11 family. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0250 family. | 0.708 |
dacC | lipA | PSEEN4822 | PSEEN4819 | D-ala-D-ala-carboxypeptidase; Function of strongly homologous gene; enzyme; Belongs to the peptidase S11 family. | Lipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.630 |
dacC | lipB | PSEEN4822 | PSEEN4820 | D-ala-D-ala-carboxypeptidase; Function of strongly homologous gene; enzyme; Belongs to the peptidase S11 family. | Lipoyl(octanyl)-acyl carrier protein: protein transferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.630 |
gcvH-1 | bkdB | PSEEN5308 | PSEEN3855 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 2-oxoisovalerate dehydrogenase, lipoamide acyltransferase component; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.644 |
gcvH-1 | gcvH-2 | PSEEN5308 | PSEEN4435 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.904 |
gcvH-1 | lipA | PSEEN5308 | PSEEN4819 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Lipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.827 |
gcvH-1 | lipB | PSEEN5308 | PSEEN4820 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Lipoyl(octanyl)-acyl carrier protein: protein transferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.768 |
gcvH-1 | lpd3 | PSEEN5308 | PSEEN5519 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Dihydrolipoamide dehydrogenase 3; Function of strongly homologous gene; enzyme. | 0.963 |
gcvH-1 | lpdV | PSEEN5308 | PSEEN3856 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 2-oxoisovalerate dehydrogenase, lipoamide dehydrogenase component; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.967 |
gcvH-1 | sucB | PSEEN5308 | PSEEN3639 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 2-oxoglutarate dehydrogenase, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.587 |
gcvH-2 | bkdB | PSEEN4435 | PSEEN3855 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 2-oxoisovalerate dehydrogenase, lipoamide acyltransferase component; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.636 |