node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PSEEN1364 | PSEEN1365 | PSEEN1364 | PSEEN1365 | Putative GTP pyrophosphokinase RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.969 |
PSEEN1364 | cyaA | PSEEN1364 | PSEEN5359 | Putative GTP pyrophosphokinase RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Adenylate cyclase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.901 |
PSEEN1364 | folE2 | PSEEN1364 | PSEEN1521 | Putative GTP pyrophosphokinase RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | GTP cyclohydrolase I; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 0.800 |
PSEEN1364 | ndk | PSEEN1364 | PSEEN1017 | Putative GTP pyrophosphokinase RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.912 |
PSEEN1364 | pykA | PSEEN1364 | PSEEN1147 | Putative GTP pyrophosphokinase RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Pyruvate kinase II, glucose-stimulated; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the pyruvate kinase family. | 0.906 |
PSEEN1364 | pykF | PSEEN1364 | PSEEN1668 | Putative GTP pyrophosphokinase RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Pyruvate kinase I; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the pyruvate kinase family. | 0.906 |
PSEEN1364 | ribA | PSEEN1364 | PSEEN0596 | Putative GTP pyrophosphokinase RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.810 |
PSEEN1364 | ribB/A | PSEEN1364 | PSEEN0590 | Putative GTP pyrophosphokinase RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.829 |
PSEEN1364 | spoT | PSEEN1364 | PSEEN5447 | Putative GTP pyrophosphokinase RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.914 |
PSEEN1365 | PSEEN1364 | PSEEN1365 | PSEEN1364 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Putative GTP pyrophosphokinase RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.969 |
PSEEN1365 | cpdA | PSEEN1365 | PSEEN4971 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Putative metallo-phosphoesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.918 |
PSEEN1365 | cyaA | PSEEN1365 | PSEEN5359 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Adenylate cyclase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.900 |
PSEEN1365 | folE2 | PSEEN1365 | PSEEN1521 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | GTP cyclohydrolase I; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 0.824 |
PSEEN1365 | ndk | PSEEN1365 | PSEEN1017 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.900 |
PSEEN1365 | pykA | PSEEN1365 | PSEEN1147 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Pyruvate kinase II, glucose-stimulated; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the pyruvate kinase family. | 0.900 |
PSEEN1365 | pykF | PSEEN1365 | PSEEN1668 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Pyruvate kinase I; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the pyruvate kinase family. | 0.900 |
PSEEN1365 | ribA | PSEEN1365 | PSEEN0596 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.800 |
PSEEN1365 | ribB/A | PSEEN1365 | PSEEN0590 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.818 |
PSEEN1365 | spoT | PSEEN1365 | PSEEN5447 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.918 |
cpdA | PSEEN1365 | PSEEN4971 | PSEEN1365 | Putative metallo-phosphoesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.918 |