node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PSEEN0389 | aroA | PSEEN0389 | PSEEN1490 | Putative chorismate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Putative prephenate dehydrogenase, putative/3-phosphoshikimate 1-carboxyvinyltransferase AroA; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.987 |
PSEEN0389 | pheA | PSEEN0389 | PSEEN1489 | Putative chorismate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Bifunctional chorismate mutase/prephenate dehydratase PheA; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.921 |
PSEEN0389 | pmsC | PSEEN0389 | PSEEN2504 | Putative chorismate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Isochorismate synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.874 |
PSEEN0389 | trpE | PSEEN0389 | PSEEN0444 | Putative chorismate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.913 |
PSEEN0389 | ubiC1 | PSEEN0389 | PSEEN4753 | Putative chorismate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Putative chorismate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. | 0.867 |
PSEEN0389 | ubiC2 | PSEEN0389 | PSEEN5461 | Putative chorismate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Putative chorismate-pyruvate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. | 0.816 |
PSEEN2640 | PSEEN4091 | PSEEN2640 | PSEEN4091 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Putative thioesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 0.905 |
PSEEN2640 | ubiA | PSEEN2640 | PSEEN5462 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 4-hydroxybenzoate octaprenyltransferase (4-HB polyprenyltransferase); Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.900 |
PSEEN2640 | ubiC1 | PSEEN2640 | PSEEN4753 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Putative chorismate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. | 0.914 |
PSEEN2640 | ubiC2 | PSEEN2640 | PSEEN5461 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Putative chorismate-pyruvate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. | 0.914 |
PSEEN4091 | PSEEN2640 | PSEEN4091 | PSEEN2640 | Putative thioesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.905 |
PSEEN4091 | ubiA | PSEEN4091 | PSEEN5462 | Putative thioesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 4-hydroxybenzoate octaprenyltransferase (4-HB polyprenyltransferase); Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.905 |
PSEEN4091 | ubiC1 | PSEEN4091 | PSEEN4753 | Putative thioesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Putative chorismate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. | 0.903 |
PSEEN4091 | ubiC2 | PSEEN4091 | PSEEN5461 | Putative thioesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Putative chorismate-pyruvate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. | 0.903 |
aroA | PSEEN0389 | PSEEN1490 | PSEEN0389 | Putative prephenate dehydrogenase, putative/3-phosphoshikimate 1-carboxyvinyltransferase AroA; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Putative chorismate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 0.987 |
aroA | hisC | PSEEN1490 | PSEEN1108 | Putative prephenate dehydrogenase, putative/3-phosphoshikimate 1-carboxyvinyltransferase AroA; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Histidinol-phosphate aminotransferase; Function of strongly homologous gene; enzyme; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.995 |
aroA | pheA | PSEEN1490 | PSEEN1489 | Putative prephenate dehydrogenase, putative/3-phosphoshikimate 1-carboxyvinyltransferase AroA; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Bifunctional chorismate mutase/prephenate dehydratase PheA; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.998 |
aroA | pmsC | PSEEN1490 | PSEEN2504 | Putative prephenate dehydrogenase, putative/3-phosphoshikimate 1-carboxyvinyltransferase AroA; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Isochorismate synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.889 |
aroA | trpE | PSEEN1490 | PSEEN0444 | Putative prephenate dehydrogenase, putative/3-phosphoshikimate 1-carboxyvinyltransferase AroA; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.654 |
aroA | ubiC1 | PSEEN1490 | PSEEN4753 | Putative prephenate dehydrogenase, putative/3-phosphoshikimate 1-carboxyvinyltransferase AroA; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Putative chorismate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. | 0.877 |