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GLYMA02G41870.2 protein (Glycine max) - STRING interaction network
"GLYMA02G41870.2" - Folylpolyglutamate synthase in Glycine max
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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GLYMA02G41870.2Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family (544 aa)    
Predicted Functional Partners:
GLYMA02G13270.3
Uncharacterized protein (523 aa)
   
 
  0.963
GLYMA13G34300.1
Uncharacterized protein (342 aa)
         
  0.955
LOC547881
Gamma-glutamyl hydrolase (348 aa)
         
  0.955
GLYMA12G04480.2
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism (580 aa)
   
 
  0.936
GLYMA11G12280.2
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism (618 aa)
   
 
  0.936
DHFR-TS
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Can play two different roles depending on the source of dihydrofolate- de novo synthesis of tetrahydrofolate or recycling of the dihydrofolate released as one of the end products of the TS catalyzed reaction. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity) (568 aa)
   
 
  0.936
GLYMA04G01244.2
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism (530 aa)
   
 
  0.936
USP1
UDP-sugar pyrophosphorylase 1; May function as the terminal enzyme of the myo-inositol oxidation (MIO) pathway. May also play a role in the salvage pathway for synthesis of nucleotide sugars (633 aa)
     
   
  0.788
GLYMA08G06790.1
Uncharacterized protein (458 aa)
     
   
  0.773
GLYMA07G30460.1
Uncharacterized protein (458 aa)
     
   
  0.773
Your Current Organism:
Glycine max
NCBI taxonomy Id: 3847
Other names: G. max, Glycine max, Glycine max (L.) Merr., soybean, soybeans
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