STRINGSTRING
TOP3A protein (Glycine max) - STRING interaction network
"TOP3A" - DNA topoisomerase 3-alpha in Glycine max
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurence
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[Homology]
Score
TOP3ADNA topoisomerase 3-alpha; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5’-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3’-OH DNA strand (913 aa)    
Predicted Functional Partners:
GLYMA06G23580.2
Uncharacterized protein (448 aa)
     
  0.971
GLYMA04G21826.1
Uncharacterized protein (209 aa)
     
  0.971
GLYMA09G08180.1
Uncharacterized protein (737 aa)
   
  0.969
GLYMA12G29151.1
Uncharacterized protein (1152 aa)
   
  0.965
GLYMA08G20070.1
Uncharacterized protein (1160 aa)
   
  0.965
GLYMA20G37970.3
Uncharacterized protein (854 aa)
   
  0.965
GLYMA18G40521.1
Putative helicase (75 aa)
   
  0.965
GLYMA18G05562.1
Uncharacterized protein (920 aa)
   
  0.965
GLYMA15G19681.1
Uncharacterized protein (287 aa)
   
  0.965
GLYMA11G31721.1
Uncharacterized protein (974 aa)
   
  0.965
Your Current Organism:
Glycine max
NCBI taxonomy Id: 3847
Other names: Fabaceae, Fabales, Faboideae, G. max, Glycine, Glycine max, Glycine max (L.) Merr., Leguminosae, Papilionoideae, Phaseoleae, pea family, soybean, soybeans
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