STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rsbWSerine/threonine-protein kinase rsbw; Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B) (157 aa)    
Predicted Functional Partners:
rsbV
Belongs to the anti-sigma-factor antagonist family
 
 
 0.998
sigB
Rna polymerase sigma-37 (sigma-b); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
 
 
 0.995
rsbX
annotation not available
 
 
 
 0.978
rsbU
annotation not available
 
 
 
 0.961
rsbS
annotation not available
 
 
 0.943
rsbT
annotation not available
 
   
 0.927
rsbR
annotation not available
 
 
 0.912
lwe0870
Pemk family transcriptional regulator; Toxic component of a type II toxin-antitoxin (TA) system
 
   
 0.597
lwe0757
annotation not available
 
 
 0.512
lwe1658
annotation not available
 
 
 0.512
Your Current Organism:
Listeria welshimeri
NCBI taxonomy Id: 386043
Other names: L. welshimeri serovar 6b str. SLCC5334, Listeria welshimeri serovar 6b str. SLCC5334, Listeria welshimeri serovar 6b strain SLCC5334
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