node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ezrA | lwe1012 | lwe1607 | lwe1012 | Septation ring formation regulator; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. | Conserved hypothetical protein; Belongs to the UPF0356 family. | 0.667 |
ezrA | lwe1618 | lwe1607 | lwe1618 | Septation ring formation regulator; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. | Conserved hypothetical protein. | 0.744 |
ezrA | lwe1624 | lwe1607 | lwe1624 | Septation ring formation regulator; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. | Conserved hypothetical protein; Belongs to the UPF0354 family. | 0.702 |
ezrA | rpoE | lwe1607 | lwe2510 | Septation ring formation regulator; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. | DNA-directed RNA polymerase, delta subunit; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family. | 0.499 |
ezrA | spx | lwe1607 | lwe2208 | Septation ring formation regulator; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. | Regulatory protein Spx; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily. | 0.530 |
lwe1012 | ezrA | lwe1012 | lwe1607 | Conserved hypothetical protein; Belongs to the UPF0356 family. | Septation ring formation regulator; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. | 0.667 |
lwe1012 | lwe1035 | lwe1012 | lwe1035 | Conserved hypothetical protein; Belongs to the UPF0356 family. | Conserved hypothetical protein; Belongs to the UPF0223 family. | 0.737 |
lwe1012 | lwe1618 | lwe1012 | lwe1618 | Conserved hypothetical protein; Belongs to the UPF0356 family. | Conserved hypothetical protein. | 0.708 |
lwe1012 | lwe1624 | lwe1012 | lwe1624 | Conserved hypothetical protein; Belongs to the UPF0356 family. | Conserved hypothetical protein; Belongs to the UPF0354 family. | 0.644 |
lwe1012 | rnj | lwe1012 | lwe1011 | Conserved hypothetical protein; Belongs to the UPF0356 family. | Metallo-beta-lactamase family protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily. | 0.923 |
lwe1012 | rpoA | lwe1012 | lwe2556 | Conserved hypothetical protein; Belongs to the UPF0356 family. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.756 |
lwe1012 | rpoB | lwe1012 | lwe0227 | Conserved hypothetical protein; Belongs to the UPF0356 family. | DNA-directed RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.756 |
lwe1012 | rpoC | lwe1012 | lwe0228 | Conserved hypothetical protein; Belongs to the UPF0356 family. | RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.756 |
lwe1012 | rpoE | lwe1012 | lwe2510 | Conserved hypothetical protein; Belongs to the UPF0356 family. | DNA-directed RNA polymerase, delta subunit; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family. | 0.739 |
lwe1012 | spx | lwe1012 | lwe2208 | Conserved hypothetical protein; Belongs to the UPF0356 family. | Regulatory protein Spx; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily. | 0.644 |
lwe1035 | lwe1012 | lwe1035 | lwe1012 | Conserved hypothetical protein; Belongs to the UPF0223 family. | Conserved hypothetical protein; Belongs to the UPF0356 family. | 0.737 |
lwe1035 | lwe1618 | lwe1035 | lwe1618 | Conserved hypothetical protein; Belongs to the UPF0223 family. | Conserved hypothetical protein. | 0.451 |
lwe1618 | ezrA | lwe1618 | lwe1607 | Conserved hypothetical protein. | Septation ring formation regulator; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. | 0.744 |
lwe1618 | lwe1012 | lwe1618 | lwe1012 | Conserved hypothetical protein. | Conserved hypothetical protein; Belongs to the UPF0356 family. | 0.708 |
lwe1618 | lwe1035 | lwe1618 | lwe1035 | Conserved hypothetical protein. | Conserved hypothetical protein; Belongs to the UPF0223 family. | 0.451 |