node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
era | lwe1482 | lwe1477 | lwe1482 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Phosphate starvation induced PhoH family protein. | 0.862 |
era | recO | lwe1477 | lwe1475 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Recombination protein O; Involved in DNA repair and RecF pathway recombination. | 0.710 |
era | rncS | lwe1477 | lwe1824 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.673 |
era | topA | lwe1477 | lwe1292 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.528 |
era | topB | lwe1477 | lwe2703 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...] | 0.528 |
lwe0902 | recO | lwe0902 | lwe1475 | ABC transporter, ATP-binding protein. | Recombination protein O; Involved in DNA repair and RecF pathway recombination. | 0.566 |
lwe1482 | era | lwe1482 | lwe1477 | Phosphate starvation induced PhoH family protein. | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.862 |
lwe1482 | recO | lwe1482 | lwe1475 | Phosphate starvation induced PhoH family protein. | Recombination protein O; Involved in DNA repair and RecF pathway recombination. | 0.727 |
lwe1495 | recJ | lwe1495 | lwe1538 | comEC/Rec2 family protein. | single-stranded-DNA-specific exonuclease RecJ. | 0.619 |
lwe1495 | recO | lwe1495 | lwe1475 | comEC/Rec2 family protein. | Recombination protein O; Involved in DNA repair and RecF pathway recombination. | 0.570 |
lwe1495 | recX | lwe1495 | lwe1711 | comEC/Rec2 family protein. | Regulatory protein, putative; Modulates RecA activity; Belongs to the RecX family. | 0.522 |
recJ | lwe1495 | lwe1538 | lwe1495 | single-stranded-DNA-specific exonuclease RecJ. | comEC/Rec2 family protein. | 0.619 |
recJ | recO | lwe1538 | lwe1475 | single-stranded-DNA-specific exonuclease RecJ. | Recombination protein O; Involved in DNA repair and RecF pathway recombination. | 0.606 |
recJ | recR | lwe1538 | lwe2653 | single-stranded-DNA-specific exonuclease RecJ. | Recombination protein; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.569 |
recJ | recX | lwe1538 | lwe1711 | single-stranded-DNA-specific exonuclease RecJ. | Regulatory protein, putative; Modulates RecA activity; Belongs to the RecX family. | 0.573 |
recJ | topA | lwe1538 | lwe1292 | single-stranded-DNA-specific exonuclease RecJ. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.675 |
recJ | topB | lwe1538 | lwe2703 | single-stranded-DNA-specific exonuclease RecJ. | DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...] | 0.616 |
recO | era | lwe1475 | lwe1477 | Recombination protein O; Involved in DNA repair and RecF pathway recombination. | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.710 |
recO | lwe0902 | lwe1475 | lwe0902 | Recombination protein O; Involved in DNA repair and RecF pathway recombination. | ABC transporter, ATP-binding protein. | 0.566 |
recO | lwe1482 | lwe1475 | lwe1482 | Recombination protein O; Involved in DNA repair and RecF pathway recombination. | Phosphate starvation induced PhoH family protein. | 0.727 |