STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metKS-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (399 aa)    
Predicted Functional Partners:
lwe1696
Homocysteine S-methyltransferase family/methylenetetrahydrofolate reductase family protein.
  
 
 0.981
metE
Similar to 5-methyltetrahydrofolate-homocysteine methyltransferase (metH); Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
  
 0.967
lwe0838
vitamin-B12 independent methionine synthase family protein.
  
 0.959
lcmA
Cytosine methyl transferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
    
 0.928
lwe1761
Conserved hypothetical protein.
   
 0.925
lwe0260
Aminotransferase, class I / II.
  
 0.923
lwe1608
GAF domain protein.
     
  0.900
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
 
  
 0.741
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
 
  
 0.737
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
 
   
 0.715
Your Current Organism:
Listeria welshimeri
NCBI taxonomy Id: 386043
Other names: L. welshimeri serovar 6b str. SLCC5334, Listeria welshimeri serovar 6b str. SLCC5334, Listeria welshimeri serovar 6b strain SLCC5334
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