node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
apt | deoD | lwe1537 | lwe1875 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Purine nucleoside phosphorylase. | 0.914 |
apt | lwe0112 | lwe1537 | lwe0112 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Putative 5'-nucleotidase, peptidoglycan bound protein (LPXTG motif). | 0.908 |
apt | lwe1979 | lwe1537 | lwe1979 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.925 |
apt | tilS | lwe1537 | lwe0182 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Conserved hypothetical/hypoxanthine phosphoribosyltransferase, fusion protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.939 |
cdd | deoD | lwe1478 | lwe1875 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Purine nucleoside phosphorylase. | 0.936 |
cdd | lwe0112 | lwe1478 | lwe0112 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Putative 5'-nucleotidase, peptidoglycan bound protein (LPXTG motif). | 0.909 |
cdd | lwe1979 | lwe1478 | lwe1979 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.938 |
cdd | pdp | lwe1478 | lwe2013 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Pyrimidine-nucleoside phosphorylase. | 0.993 |
cdd | tdk | lwe1478 | lwe2493 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Thymidine kinase. | 0.939 |
cdd | tilS | lwe1478 | lwe0182 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Conserved hypothetical/hypoxanthine phosphoribosyltransferase, fusion protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.497 |
cdd | upp | lwe1478 | lwe2487 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.472 |
cobB | deoD | lwe2687 | lwe1875 | Transcriptional regulator, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. | Purine nucleoside phosphorylase. | 0.930 |
cobB | lwe1979 | lwe2687 | lwe1979 | Transcriptional regulator, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. | Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.911 |
deoD | apt | lwe1875 | lwe1537 | Purine nucleoside phosphorylase. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.914 |
deoD | cdd | lwe1875 | lwe1478 | Purine nucleoside phosphorylase. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.936 |
deoD | cobB | lwe1875 | lwe2687 | Purine nucleoside phosphorylase. | Transcriptional regulator, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. | 0.930 |
deoD | lwe0112 | lwe1875 | lwe0112 | Purine nucleoside phosphorylase. | Putative 5'-nucleotidase, peptidoglycan bound protein (LPXTG motif). | 0.916 |
deoD | lwe1979 | lwe1875 | lwe1979 | Purine nucleoside phosphorylase. | Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.936 |
deoD | pdp | lwe1875 | lwe2013 | Purine nucleoside phosphorylase. | Pyrimidine-nucleoside phosphorylase. | 0.950 |
deoD | pncB | lwe1875 | lwe1067 | Purine nucleoside phosphorylase. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.913 |