STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABK61035.1Stage II sporulation protein E; Identified by match to protein family HMM PF07228. (798 aa)    
Predicted Functional Partners:
ABK61443.1
Sporulation factor SpoIIGA; Identified by match to protein family HMM PF03419.
  
  
 0.955
ABK62261.1
Stage II sporulation protein P; Identified by match to protein family HMM PF07454.
  
   
 0.904
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.900
ABK62525.1
Stage II sporulation protein R.
  
   
 0.890
ABK61238.1
RNA polymerase sigma-E factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.860
ABK60597.1
Specialized DNA-dependent RNA polymerase sigma subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.856
spoIIID
Stage III sporulation protein D.
  
   
 0.852
ABK61161.1
Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
  
 0.850
ABK61524.1
Stage III sporulation protein AA, SpoIIIAA.
  
   
 0.817
ABK61150.1
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
   
 0.817
Your Current Organism:
Clostridium novyi
NCBI taxonomy Id: 386415
Other names: C. novyi NT, Clostridium novyi NT, Clostridium novyi str. NT, Clostridium novyi strain NT, Clostridium novyi-NT
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