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hisE protein (Clostridium novyi NT) - STRING interaction network
"hisE" - Phosphoribosyl-ATP pyrophosphatase in Clostridium novyi NT
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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hisEPhosphoribosyl-ATP pyrophosphatase; Identified by match to protein family HMM PF01503 (110 aa)    
Predicted Functional Partners:
hisF
Multifunctional fusion protein; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP; Belongs to the PRA-CH family (358 aa)
   
  0.998
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N’-(5’-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity; Belongs to the ATP phosphoribosyltransferase family. Short subfamily (212 aa)
 
 
  0.997
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (430 aa)
 
   
  0.987
hisA
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Identified by match to protein family HMM PF00977; match to protein family HMM TIGR00007 (238 aa)
 
   
  0.984
hisZ
ATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (421 aa)
 
   
  0.983
hisB
Imidazoleglycerol-phosphate dehydratase; Identified by match to protein family HMM PF00475 (196 aa)
 
   
  0.978
hisC
Histidinol-phosphate aminotransferase; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01141; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily (356 aa)
 
   
  0.920
ABK61675.1
5-methyltetrahydrofolate--homocysteine methyltransferase, putative; Identified by match to protein family HMM PF00809; match to protein family HMM PF02310; match to protein family HMM PF02574; match to protein family HMM PF02607 (808 aa)
         
  0.780
ABK61670.1
L-threonine-O-3-phosphate decarboxylase, putative; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01140 (353 aa)
 
   
  0.610
ribBA
Riboflavin biosynthesis protein RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family (414 aa)
   
   
  0.483
Your Current Organism:
Clostridium novyi NT
NCBI taxonomy Id: 386415
Other names: C. novyi NT, Clostridium novyi NT, Clostridium novyi str. NT, Clostridium novyi strain NT, Clostridium novyi-NT
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