STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mcsBHypothetical ATP:guanido phosphotransferase; Catalyzes the specific phosphorylation of arginine residues in proteins; Belongs to the ATP:guanido phosphotransferase family. (344 aa)    
Predicted Functional Partners:
ABK60915.1
Conserved hypothetical protein; Identified by match to protein family HMM PF02151.
 
  
 0.995
ABK60629.1
Transcription regulator ctsR; Identified by match to protein family HMM PF05848; Belongs to the CtsR family.
 
  
 0.960
ABK61897.1
Negative regulator of genetic competence clpC/mecB; Identified by match to protein family HMM PF00004; match to protein family HMM PF02151; match to protein family HMM PF02861; Belongs to the ClpA/ClpB family.
 
 
 0.941
radA
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
  
    0.765
ABK62513.1
Putative low molecular weight protein-tyrosine-phosphatase; Identified by match to protein family HMM PF01451; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
  
  
 0.709
disA
Domain of unknown function DUF147 family protein; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
  
    0.665
clpB
clpB protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
  
 
 0.661
ABK60429.1
Negative regulator of genetic competence clpC/mecB; Identified by match to protein family HMM PF00004; Belongs to the ClpA/ClpB family.
  
 
 0.642
ABK61860.1
ATP-dependent Clp protease, ATPase subunit, putative.
  
 
 0.642
clpP
ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
   
  
 0.471
Your Current Organism:
Clostridium novyi
NCBI taxonomy Id: 386415
Other names: C. novyi NT, Clostridium novyi NT, Clostridium novyi str. NT, Clostridium novyi strain NT, Clostridium novyi-NT
Server load: medium (68%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.